Anti-ZBRK1抗体(ab77085)
Key features and details
- Rabbit polyclonal to ZBRK1
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
概述
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产品名称
Anti-ZBRK1抗体 -
描述
兔多克隆抗体to ZBRK1 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse -
免疫原
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C. -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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ChIP Related Products
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab77085于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB | (3) |
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 60 kDa.
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说明 |
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WB
Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 60 kDa. |
靶标
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功能
Transcriptional repressor. Binds to a specific sequence, 5'-GGGxxxCAGxxxTTT-3', within GADD45 intron 3. -
组织特异性
Widely expressed. -
序列相似性
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 8 C2H2-type zinc fingers.
Contains 1 KRAB domain. -
细胞定位
Nucleus matrix. Associated with the nuclear matrix. - Information by UniProt
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数据库链接
- Entrez Gene: 234358 Mouse
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别名
- KRAB zinc finger protein ZFQR antibody
- ZBRK1 antibody
- ZFQR antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab77085 被引用在 3 文献中.
- Chen K et al. ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancer. Oncotarget 6:6959-76 (2015). IF . PubMed: 25749518
- Calderon MR et al. Ligand-dependent corepressor contributes to transcriptional repression by C2H2 zinc-finger transcription factor ZBRK1 through association with KRAB-associated protein-1. Nucleic Acids Res 42:7012-27 (2014). ChIP . PubMed: 24829459
- Hallen L et al. The KRAB-containing zinc-finger transcriptional regulator ZBRK1 activates SCA2 gene transcription through direct interaction with its gene product, ataxin-2. Hum Mol Genet : (2010). WB, ChIP ; Human . PubMed: 20926453