概述

  • 产品名称
  • 描述
    兔多克隆抗体to ZMYM2
  • 特异性
    At least three isoforms of ZMYM2 are known to exist; ab106624 will detect only the longest isoform. It is predicted to not cross react with other ZMYM protein family members.
  • 经测试应用
    适用于: ICC/IF, WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    A 17 amino acid peptide near the amino terminus of Human ZMYM2 (CAH71822).

  • 阳性对照
    • EL4 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab106624 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ICC/IF Use a concentration of 10 µg/ml.
WB Use a concentration of 0.125 - 0.25 µg/ml. Predicted molecular weight: 155 kDa.

靶标

  • 功能
    May function as a transcription factor.
  • 疾病相关
    Note=A chromosomal aberration involving ZMYM2 may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Translocation t(8;13)(p11;q12) with FGFR1. SCLL usually presents as lymphoblastic lymphoma in association with a myeloproliferative disorder, often accompanied by pronounced peripheral eosinophilia and/or prominent eosinophilic infiltrates in the affected bone marrow.
  • 序列相似性
    Contains 9 MYM-type zinc fingers.
  • 细胞定位
    Nucleus.
  • Information by UniProt
  • 数据库链接
  • 形式
    There are 2 isoforms produced by alternative splicing.
  • 别名
    • FIM antibody
    • Fused in myeloproliferative disorders protein antibody
    • MYM antibody
    • RAMP antibody
    • Rearranged in an atypical myeloproliferative disorder antibody
    • Rearranged in atypical myeloproliferative disorder protein antibody
    • SCLL antibody
    • ZFP 198 antibody
    • Zinc finger MYM type containing 2 antibody
    • Zinc finger MYM type protein 2 antibody
    • Zinc finger MYM-type protein 2 antibody
    • Zinc finger protein 198 antibody
    • Zinc finger protein198 antibody
    • zinc finger, MYM-type 2 antibody
    • ZMYM 2 antibody
    • ZMYM2 antibody
    • ZMYM2_HUMAN antibody
    • ZNF 198 antibody
    • ZNF198 antibody
    see all

Anti-ZMYM2 antibody 图像

  • Immunofluorescence of ZMYM2 in HeLa cells with ab106624 at 20 ug/mL.
  • Lane 1 : Anti-ZMYM2 antibody (ab106624) at 0.125 µg/ml
    Lane 2 : Anti-ZMYM2 antibody (ab106624) at 0.25 µg/ml

    Lane 1 : EL4 cell lysate
    Lane 2 : EL4 cell lysate

    Lysates/proteins at 15 µg per lane.


    Predicted band size : 155 kDa
  • Immunocytochemistry of ZMYM2 in HeLa cells with ab106624 at 10 ug/mL.

Anti-ZMYM2 antibody (ab106624)参考文献

ab106624 has not yet been referenced specifically in any publications.

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