Anti-ZMYM2/RAMP抗体(ab106624)
Key features and details
- Rabbit polyclonal to ZMYM2/RAMP
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
概述
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产品名称
Anti-ZMYM2/RAMP抗体 -
描述
兔多克隆抗体to ZMYM2/RAMP -
宿主
Rabbit -
特异性
At least three isoforms of ZMYM2/RAMP are known to exist; ab106624 will detect only the longest isoform. It is predicted to not cross react with other ZMYM protein family members.
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经测试应用
适用于: WBmore details -
种属反应性
与反应: Mouse -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- EL4 cell lysate
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at 4°C (stable for up to 12 months). -
存储溶液
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab106624于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
Use a concentration of 0.125 - 0.25 µg/ml. Predicted molecular weight: 155 kDa.
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说明 |
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WB
Use a concentration of 0.125 - 0.25 µg/ml. Predicted molecular weight: 155 kDa. |
靶标
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功能
May function as a transcription factor. -
疾病相关
Note=A chromosomal aberration involving ZMYM2 may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Translocation t(8;13)(p11;q12) with FGFR1. SCLL usually presents as lymphoblastic lymphoma in association with a myeloproliferative disorder, often accompanied by pronounced peripheral eosinophilia and/or prominent eosinophilic infiltrates in the affected bone marrow. -
序列相似性
Contains 9 MYM-type zinc fingers. -
细胞定位
Nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 76007 Mouse
- SwissProt: Q9CU65 Mouse
- Unigene: 31417 Mouse
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形式
There are 2 isoforms produced by alternative splicing. -
别名
- FIM antibody
- Fused in myeloproliferative disorders protein antibody
- MYM antibody
see all
图片
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (3)
ab106624 被引用在 3 文献中.
- Meijer BJ et al. Endoplasmic reticulum stress regulates the intestinal stem cell state through CtBP2. Sci Rep 11:9892 (2021). PubMed: 33972635
- Cibis H et al. Characterization of the zinc finger proteins ZMYM2 and ZMYM4 as novel B-MYB binding proteins. Sci Rep 10:8390 (2020). PubMed: 32439918
- Connaughton DM et al. Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations. Am J Hum Genet 107:727-742 (2020). PubMed: 32891193