概述

  • 产品名称ZM 336372
  • 描述
    Potent, selective c-Raf inhibitor
  • 生物学描述Potent, cell-permeable and selective c-Raf inhibitor (IC50 = 70 nM). Displays 10-fold selectivity over b-Raf. Inhibits carcinoid cell growth. Also inhibits growth and apoptosis in pancreatic cancer cells.
  • 纯度> 98%

性能

    ZM 336372 (ab120428)参考文献

    This product has been referenced in:
    • Deming D  et al. ZM336372 induces apoptosis associated with phosphorylation of GSK-3beta in pancreatic adenocarcinoma cell lines. J Surg Res 161:28-32 (2010). Read more (PubMed: 20031160) »
    • Kunnimalaiyaan M  et al. Neuroendocrine tumor cell growth inhibition by ZM336372 through alterations in multiple signaling pathways. Surgery 142:959-64; discussion 959-64 (2007). Read more (PubMed: 18063082) »
    • Hall-Jackson CA  et al. Paradoxical activation of Raf by a novel Raf inhibitor. Chem Biol 6:559-68 (1999). Read more (PubMed: 10421767) »

    See 0 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab120428.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"