概述

性能

应用

Our Abpromise guarantee covers the use of ab58318 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'.
    • 疾病相关Heterotaxy, visceral, 1, X-linked
      VACTERL association X-linked with or without hydrocephalus
      Congenital heart defects, multiple types, 1, X-linked
    • 序列相似性Belongs to the GLI C2H2-type zinc-finger protein family.
      Contains 5 C2H2-type zinc fingers.
    • 结构域The C2H2-type 3, 4 and 5 zinc finger domains are necessary for transcription activation.
    • 细胞定位Nucleus. Cytoplasm. Localizes in the cytoplasm in presence of MDFIC overexpression (By similarity). Translocation to the nucleus requires KPNA1 or KPNA6.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Heterotaxy 1 antibody
      • HTX antibody
      • HTX1 antibody
      • ZIC 3 antibody
      • Zic family member 3 (odd paired Drosophila homolog heterotaxy 1) antibody
      • Zic family member 3 antibody
      • Zic3 antibody
      • ZIC3_HUMAN antibody
      • Zinc finger protein 203 antibody
      • Zinc finger protein of the cerebellum 3 antibody
      • Zinc finger protein ZIC 3 (Zinc finger protein of the cerebellum 3) antibody
      • Zinc finger protein ZIC 3 antibody
      • ZNF203 antibody
      see all

    Anti-ZIC3 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab58318 Zic 3 antibody at 1ug/ml. Predicted band size of immunogen is 36 kDa

    Anti-ZIC3 antibody (ab58318)参考文献

    ab58318 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab58318.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"