KLH conjugated synthetic peptide corresponding to a region within C terminal amino acids 611-642 of Human ZFYVE28 (NP_001166130.1, NP_001166131.1, NP_066023.2, NP_001166127.1, NP_001166129.1).
- Mouse heart tissue lysate
- 存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
- 存储溶液Preservative: 0.09% Sodium Azide
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- 纯度Immunogen affinity purified
- 纯化说明ab107913 is purified through a protein A column, followed by peptide affinity purification.
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||1/100 - 1/500. Predicted molecular weight: 96 kDa.
- 功能Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated.
- 序列相似性Belongs to the lst-2 family.
Contains 1 FYVE-type zinc finger.
- 结构域The FYVE-type zinc finger mediates the interaction with phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes when not monoubiquitinated at Lys-87.
- 翻译后修饰Monoubiquitination at Lys-87 prevents binding to phosphatidylinositol 3-phosphate (PI3P) and localization to early endosome membranes.
- 细胞定位Cytoplasm > cytosol. Early endosome membrane. Localizes to early endosome membrane in absence of Lys-87 monoubiquitination. Localizes to cytosol when monoubiquitinated.
Information by UniProt
- hLst2 antibody
- Lateral signaling target protein 2 homolog antibody
- LST2 antibody
Anti-ZFYVE28 antibody (ab107913)参考文献
has not yet been referenced specifically in any publications.
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