The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Detects a band of approximately 30 kDa (predicted molecular weight: 27 kDa).
功能Plays a role in cell adhesion, and thereby in cell motility, regulating microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassemblya, as well as integrin beta-1/ITGB1 cell surface expression.
序列相似性Contains 1 FYVE-type zinc finger.
细胞定位Cell junction > focal adhesion. Cytoplasmic vesicle. Within cytoplasmic vesicles, partially colocalizes with EEA1, an endosomal marker.