概述

  • 产品名称Anti-ZFYVE16抗体
    参阅全部 ZFYVE16 一抗
  • 描述
    兔多克隆抗体to ZFYVE16
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 380-410 of Human ZFYVE16 (isoform 2), conjugated to KLH.

  • 阳性对照
    • K562 cell line lysates; Human lung tissue

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab103683 is purified through a protein A column, followed by peptide affinity purification.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab103683 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: for isoform 2, 88 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes.
  • 组织特异性Widely expressed. Highly expressed in kidney, placenta and lung. Expressed at intermediate level in heart, brain, skeletal muscle, spleen and liver. Weakly expressed in colon, thymus and peripheral blood lymphocytes.
  • 序列相似性Contains 1 FYVE-type zinc finger.
  • 结构域The FYVE-type zinc finger is necessary and sufficient for its localization into early endosomes and mediates the association with PI3P.
  • 细胞定位Cytoplasm. Early endosome membrane. Localized to early endosomes. Membrane-associated, probably via its association with phosphatidylinositol 3-phosphate.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AI035632 antibody
    • B130024H06Rik antibody
    • B130031L15 antibody
    • DKFZp686E13162 antibody
    • Endofin antibody
    • Endosomal associated FYVE domain protein antibody
    • Endosome associated FYVE domain protein antibody
    • Endosome-associated FYVE domain protein antibody
    • KIAA0305 antibody
    • KIAA0305; antibody
    • mKIAA0305 antibody
    • OTTMUSP00000029589 antibody
    • RGD1564784 antibody
    • ZFY16_HUMAN antibody
    • ZFYVE16 antibody
    • Zinc finger FYVE domain containing protein 16 antibody
    • Zinc finger FYVE domain-containing protein 16 antibody
    • Zinc finger, FYVE domain containing 16 antibody
    see all

Anti-ZFYVE16 antibody 图像

  • Anti-ZFYVE16 antibody (ab103683) at 1/100 dilution + K562 cell line lysates at 35 µg

    Predicted band size : for isoform 2, 88 kDa
  • ab103683, at a 1/50 dilution, staining ZFYVE16 in formalin fixed, paraffin embedded Human lung tissue by Immunohistochemistry, followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-ZFYVE16 antibody (ab103683)参考文献

ab103683 has not yet been referenced specifically in any publications.

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