Anti-ZFP100 / ZNF473抗体(ab103023)

概述

  • 产品名称
    Anti-ZFP100 / ZNF473抗体
    参阅全部 ZFP100 / ZNF473 一抗
  • 描述
    兔多克隆抗体to ZFP100 / ZNF473
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    KLH conjugated synthetic peptide corresponding to a region within N terminal amino acids 185-215 of Human ZFP100/ ZNF473 (UniProt ID: Q8WTR7).

  • 阳性对照
    • NCI-H460 cell lysate

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab103023 is purified through a protein A column, followed by peptide affinity purification.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab103023 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 100 kDa.

靶标

  • 功能
    Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases.
  • 序列相似性
    Belongs to the krueppel C2H2-type zinc-finger protein family.
    Contains 20 C2H2-type zinc fingers.
    Contains 1 KRAB domain.
  • 结构域
    The C2H2-type zinc finger 2 to 6 are necessary and sufficient for discrete Cajal bodies localization. The C2H2-type zinc finger 5 to 10 are necessary and sufficient for interaction with LSM11. The C2H2-type zinc finger 2 to 8 are necessary for interaction with the SLBP/RNA complex in the histone pre-mRNAs. The C2H2-type zinc finger 2 to 10 confer activity in histone pre-mRNA processing.
  • 细胞定位
    Nucleus. Stable component of Cajal bodies (CBs). Colocalizes with SMN, coilin and U7 snRNA.
  • Information by UniProt
  • 数据库链接
  • 别名
    • HZFP100 antibody
    • Zfp 100 antibody
    • Zfp-100 antibody
    • Zinc finger protein 100 homolog antibody
    • Zinc finger protein 473 antibody
    • zinc finger protein ZFP100 antibody
    • ZN473_HUMAN antibody
    • Znf473 antibody
    see all

Anti-ZFP100 / ZNF473 antibody 图像

  • Anti-ZFP100 / ZNF473 antibody (ab103023) at 1/100 dilution + NCI-H460 cell lysate at 35 µg

    Predicted band size : 100 kDa

实验方案

Anti-ZFP100 / ZNF473 antibody (ab103023)参考文献

ab103023 has not yet been referenced specifically in any publications.

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