Anti-ZBTB7A抗体(ab114074)

概述

  • 产品名称Anti-ZBTB7A抗体
    参阅全部 ZBTB7A 一抗
  • 描述
    兔多克隆抗体to ZBTB7A
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Rhesus monkey
  • 免疫原

    Synthetic peptide corresponding to a region between residue 525 and the C terminus (residue 584) of Human ZBTB7A (NP_056982.1).

  • 阳性对照
    • Breast Carcinoma, Colon Carcinoma, Linitis Plastica Stomach Cancer, Lung Adenocarcinoma, Non Small Cell Lung Cancer, Ovarian Carcinoma, Placenta, Prostate Carcinoma, Stomach Adenocarcinoma.
  • 常规说明The concentration of IgG is less than or equal to 1 mg/ml.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.09% Sodium azide
    Constituents: 99% Tris buffered saline, 0.1% BSA
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明ab114074 was affinity purified using an epitope specific to ZBTB7A immobilized on a solid support.
  • 克隆多克隆
  • 同种型IgG

应用

Our Abpromise guarantee covers the use of ab114074 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100 - 1/500. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol. Antigen retrieval is recommended. Likely to work with frozen sections In some cases, the antibody may be diluted further than indicated.

靶标

  • 功能Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5'-[GA][CA]GACCCCCCCCC-3'.
  • 组织特异性Widely expressed. In normal thymus, expressed in medullary epithelial cells and Hassle's corpuscles (at protein level). In tonsil, expressed in squamous epithelium and germinal center lymphocytes (at protein level). Up-regulated in a subset of lymphomas, as well as in a subset of breast, lung, colon, prostate and bladder carcinomas (at protein level).
  • 序列相似性Contains 1 BTB (POZ) domain.
    Contains 4 C2H2-type zinc fingers.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp547O146 antibody
    • Factor binding IST protein 1 antibody
    • Factor that binds to inducer of short transcripts protein 1 antibody
    • FBI-1 antibody
    • FBI1 antibody
    • HIV-1 1st-binding protein 1 antibody
    • HIV-1 inducer of short transcripts binding protein antibody
    • HIV-1 inducer of short transcripts-binding factor 1 antibody
    • Leukemia/lymphoma-related factor antibody
    • LRF antibody
    • lymphoma related factor antibody
    • MGC99631 antibody
    • POK erythroid myeloid ontogenic factor antibody
    • Pokemon antibody
    • POZ and Krueppel erythroid myeloid ontogenic factor antibody
    • TIP21 antibody
    • TTF-I-interacting peptide 21 antibody
    • ZBT7A_HUMAN antibody
    • ZBTB7 antibody
    • ZBTB7A antibody
    • Zinc finger and BTB domain containing 7A antibody
    • zinc finger and BTB domain containing 7A, HIV-1 inducer of short transcripts binding protein antibody
    • Zinc finger and BTB domain-containing protein 7A antibody
    • Zinc finger protein 857A antibody
    • Zinc finger- and BTB domain-containing protein 7 antibody
    • ZNF857A antibody
    see all

Anti-ZBTB7A antibody 图像

  • ab114074 at 1/250 dilution staining ZBTB7A in Formalin-Fixed, Paraffin-Embedded Human Breast carcinoma tissue by Immunohistochemistry. Detection utilised DAB.
  • ab114074 at 1/250 dilution staining ZBTB7A in Formalin-Fixed, Paraffin-Embedded Human Colon carcinoma tissue by Immunohistochemistry. Detection utilised DAB.

Anti-ZBTB7A antibody (ab114074)参考文献

ab114074 has not yet been referenced specifically in any publications.

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Thank you for contacting Abcam regarding ab114074.


This antibody has not been tested in WB, therefore we do not know if or how well it will work in this application. Generally speaking, I would start by testing several dilutions, rangin...

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