概述

  • 产品名称Anti-ZAN抗体
    参阅全部 ZAN 一抗
  • 描述
    小鼠单克隆抗体to ZAN
  • 经测试应用适用于: WB, ELISA, Sandwich ELISAmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 19-114 of Human ZAN with a proprietary tag (NP_003377).

  • 阳性对照
    • Recombinant Human ZAN Protein.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液pH: 7.20
    Constituent: 99% PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆单克隆
  • 同种型IgG1
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab118116 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 306 kDa. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
ELISA Use at an assay dependent dilution.
Sandwich ELISA Use a concentration of 10 µg/ml.

靶标

  • 功能Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling.
  • 组织特异性In testis, primarily in haploid spermatids.
  • 序列相似性Contains 1 EGF-like domain.
    Contains 3 MAM domains.
    Contains 4 TIL (trypsin inhibitory-like) domains.
    Contains 5 VWFC domains.
    Contains 4 VWFD domains.
  • 结构域The MAM domains probably mediate sperm adhesion to the zona pellucida.
    During sperm migration through the reproductive tracts, the mucin-like domain might inhibit inappropriate trapping of spermatozoa or promoting adhesion to the oviductal isthmus.
    The VWFD domain 2 may mediate covalent oligomerization.
  • 细胞定位Cell membrane. Exclusively on the apical region of the sperm head.
  • Information by UniProt
  • 数据库链接
  • 别名
    • OTTHUMP00000211358 antibody
    • OTTHUMP00000211359 antibody
    • OTTHUMP00000211360 antibody
    • OTTHUMP00000211361 antibody
    • OTTHUMP00000211362 antibody
    • OTTHUMP00000211363 antibody
    • ZAN antibody
    • ZAN_HUMAN antibody
    • Zonadhesin antibody
    see all

Anti-ZAN antibody 图像

  • Anti-ZAN antibody (ab118116) at 5 µg/ml + recombinant immunogen at 0.2 µg
    Developed using the ECL technique

    Predicted band size : 306 kDa
  • ab118116 at 10 µg/ml as a capture antibody. The detection limit for recombinant tagged ZAN is 0.03 ng/ml.

Anti-ZAN antibody (ab118116)参考文献

ab118116 has not yet been referenced specifically in any publications.

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