Anti-Yersinia pestis F1 antigen抗体[1.F.1] (ab31428)

概述

  • 产品名称Anti-Yersinia pestis F1 antigen抗体[1.F.1]
    参阅全部 Yersinia pestis F1 antigen 一抗
  • 描述
    小鼠单克隆抗体[1.F.1] to Yersinia pestis F1 antigen
  • 特异性Recognizes capsule bearing strains of Y. pestis.
  • 经测试应用适用于: IHC-Fr, IHC-Pmore details
  • 种属反应性
    Reacts with Yersinia pestis Not yet tested in other species.
  • 免疫原

    Purified F1 antigen of Y. pestis vaccine strain EB.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液Preservative: 0.1% Sodium Azide
    Constituents: 40% Glycerol, PBS, pH 7.4
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号1.F.1
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab31428 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.

靶标

  • 相关性Yersinia pestis is a gram-negative coccobacillus belonging to the Enterobacteriaceae. Yersinia pestis is primarily a rodent pathogen, with humans being an accidental host when bitten by an infected rat flea.  The flea draws viable Y. pestis organisms into its intestinal tract. Some Y. pestis in the flea are then regurgitated when the flea gets its blood meal thus transferring the infection to a new host. While growing in the flea, Y. pestis loses its capsular layer, which is made of the F1 (or fraction 1) capsule antigen. Most of the organisms are phagocytosed and killed by the polymorphonuclear leukocytes in the human host. A few bacilli are taken up by tissue macrophages. The macrophages are unable to kill Y. pestis and provide a protected environment for the organisms to synthesize their virulence factors.
  • 细胞定位Secreted
  • 别名
    • Caf1 antibody
    • F1 capsule antigen antibody

Anti-Yersinia pestis F1 antigen antibody [1.F.1] (ab31428)参考文献

ab31428 has not yet been referenced specifically in any publications.

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