Anti-Yersinia pestis抗体[YPF19] (ab8275)


  • 产品名称Anti-Yersinia pestis抗体[YPF19]
  • 描述
    小鼠单克隆抗体[YPF19] to Yersinia pestis
  • 特异性This antibody recognises Y.pestis F1 capsular antigen. There is no cross-reactivity with Y.pseudotuberculosis and Y. enterocolitica.
  • 经测试应用适用于: IHC-Fr, WB, ELISAmore details
  • 免疫原

    Purified F1 antigen from Yersinia pestis vaccine strain EV76.


  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液PBS with 0.1% sodium azide, pH 7.4
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 克隆编号YPF19
  • 骨髓瘤Sp2/0
  • 同种型IgG1
  • 轻链类型unknown
  • 研究领域


Our Abpromise guarantee covers the use of ab8275 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr Use at an assay dependent concentration.
WB Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.


  • 相关性Y. pestis has a number of virulence factors that enable it to survive in humans by facilitating use of host nutrients, causing damage to host cells, and subverting phagocytosis and other host defense mechanisms. Capsular F1 antigen is a main immunochemical component of Y. pestis surface. Its synthesis is determined by pFra plasmid and induced at 370C. F1 is aggregated on the outer membrane of the Y. pestis microbe as an olygomeric protein, forming a granular layer and gradually diffusing into the environment. Capsular polymer consists of multiple similar hydrophobic protein subunits, aggregating at physiological conditions. F1 subunit of the antigen is originally synthesized from 170 amino acids and has a molecular mass 17.6 K, then, after the elimination of the signal peptide during the secretion onto the surface, a protein with molecular mass 15.6 K and isoelectric point 4.1 is formed.
  • 细胞定位Cell Membrane
  • 别名
    • Y pestis antibody
    • Y. pestis antibody
    • Y.pestis antibody

Anti-Yersinia pestis antibody [YPF19] (ab8275)参考文献

This product has been referenced in:
  • Ye Z  et al. Caspase-3 mediates the pathogenic effect of Yersinia pestis YopM in liver of C57BL/6 mice and contributes to YopM's function in spleen. PLoS One 9:e110956 (2014). IHC ; Mouse . Read more (PubMed: 25372388) »

See 1 Publication for this product

Product Wall

Thank you for contacting us.

Please find attached the CoC.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

Unfortunately we have no information concerning this question, because we have not determined that in our laboratory.

This is a very new product, and I'm afriad all the information we have is on the datasheet. The anitbody has not yet been tested in Western Blotting. A standard protocol for WB is available in the "Protocols" section of the Abcam website