概述

  • 产品名称Anti-XTP4抗体
    参阅全部 XTP4 一抗
  • 描述
    兔多克隆抗体to XTP4
  • 特异性These antibodies have been fully characterized for cross-reactivity with other members of the amplicon related proteins. Expected to cross-react with Mouse (100% identity with RIKEN cDNA 1810046J19), Rat (100% identity with similar to RIKEN cDNA 1810046J19) and Zebrafish (88% identity with "selenoprotein W2a).
  • 经测试应用适用于: ELISA, WB, IP, IHC-Frmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Zebrafish
  • 免疫原

    Synthetic peptide:

    CEIEINGQLVFSKLENGGF

    , corresponding to Internal sequence amino acids 66-83 of Human XTP4.

  • 常规说明Briefly centrifuge antibodies to collect liquid at the bottom.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab14762 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/15000 - 1/20000.
WB Use at an assay dependent concentration. Predicted molecular weight: 13.8 kDa.
IP Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.

靶标

  • 功能Increases cell migration by inducing filopodia formation at the leading edge of migrating cells. Plays a role in regulation of apoptosis, possibly through control of CASP3. May be involved in a redox-related process.
  • 组织特异性Among normal tissues, present only in Leydig cells. Strongly up-regulated in breast cancers and in brain cancer distant metastasis (at protein level). Up-regulated in prostate cancer cells and in the higher grades of prostate adenocarcinoma (at protein level).
  • 序列相似性Belongs to the SelWTH family.
  • 翻译后修饰Isoprenylation facilitates association with the plasma membrane and enhances the migratory phenotype of cells by inducing increased filopodia formation.
  • 细胞定位Cytoplasm > cytosol. Cell membrane. Concentrates at the leading edge of migrating cells. Localizes outside membrane raft regions.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C17orf37 antibody
    • C17orf37 homolog antibody
    • C35 antibody
    • chromosome 17 open reading frame 37 antibody
    • HBV X transactivated gene 4 protein antibody
    • HBV X-transactivated gene 4 protein antibody
    • HBV XAg transactivated protein 4 antibody
    • HBV XAg-transactivated protein 4 antibody
    • MGC14832 antibody
    • Mien1 antibody
    • MIEN1_HUMAN antibody
    • Migration and invasion enhancer 1 antibody
    • ORB3 antibody
    • Protein C17orf37 antibody
    • Protein C35 antibody
    • RDX12 antibody
    • Redox protein, 12-KD antibody
    • XTP4 antibody
    see all

Anti-XTP4 antibody (ab14762)参考文献

ab14762 has not yet been referenced specifically in any publications.

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