概述

  • 产品名称Anti-XRN2抗体
    参阅全部 XRN2 一抗
  • 描述
    兔多克隆抗体to XRN2
  • 经测试应用适用于: ELISA, WB, IHC-Pmore details
  • 种属反应性
    与反应: Human, African Green Monkey
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide derived from an internal sequence of human XRN2.

  • 阳性对照
    • Human breast carcinoma tissue and COS7 cell extracts.

性能

应用

Our Abpromise guarantee covers the use of ab74799 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/5000.
WB 1/500 - 1/1000. Predicted molecular weight: 109 kDa.
IHC-P 1/50 - 1/100.

靶标

  • 相关性XRN2 possesses 5'->3' exoribonuclease activity. XRN2 shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The function of the human gene has not yet been determined, however, it may promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription.
  • 细胞定位Nucleus, nucleolus.
  • 数据库链接
  • 别名
    • 5' 3' exoribonuclease 2 antibody
    • DHM1 like protein antibody
    • DHP protein antibody
    • XRN 2 antibody

Anti-XRN2 antibody 图像

  • ab74799 at 1/50 dilution staining XRN2 in human breast carcinoma by Immunohistochemistry, Paraffin-embedded tissue, in the absence or presence of the immunising peptide.
  • All lanes : Anti-XRN2 antibody (ab74799) at 1/500 dilution

    Lane 1 : COS7 cell extracts
    Lane 2 : COS7 cell extracts with immunising peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 109 kDa
    Observed band size : 109 kDa
    Additional bands at : 40 kDa. We are unsure as to the identity of these extra bands.

Anti-XRN2 antibody (ab74799)参考文献

ab74799 has not yet been referenced specifically in any publications.

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