概述

  • 产品名称Anti-XRN2抗体
    参阅全部 XRN2 一抗
  • 描述
    兔多克隆抗体to XRN2
  • 经测试应用适用于: WBmore details
    不适用于: IP
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Rabbit, Chicken, Guinea pig, Cow, Dog, Turkey, Pig, Xenopus laevis, Chimpanzee, Zebrafish, Rhesus monkey, Gorilla, Tilapia, Orangutan, Xenopus tropicalis , Medaka fish
  • 免疫原

    Synthetic peptide corresponding to a region between residue 1 and 50 of human XRN2 (NP_036387.2)

  • 阳性对照
    • Whole cell lysates from HeLa, 293T and NIH3T3 cells.

性能

应用

Our Abpromise guarantee covers the use of ab72307 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: 1/2000 - 1/10000. Detects bands of approximately 109 and 117 kDa (predicted molecular weight: 109 kDa).

    Is unsuitable for IP.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性XRN2 possesses 5'->3' exoribonuclease activity. XRN2 shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The function of the human gene has not yet been determined, however, it may promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription.
    • 细胞定位Nucleus, nucleolus.
    • 数据库链接
    • 别名
      • 5' 3' exoribonuclease 2 antibody
      • DHM1 like protein antibody
      • DHP protein antibody
      • XRN 2 antibody

    Anti-XRN2 antibody 图像

    • All lanes : Anti-XRN2 antibody (ab72307) at 0.04 µg/ml

      Lane 1 : Whole cell lysate from HeLa cells at 50 µg
      Lane 2 : Whole cell lysate from HeLa cells at 15 µg
      Lane 3 : Whole cell lysate from HeLa cells at 5 µg
      Lane 4 : Whole cell lysate from 293T cells at 50 µg
      Lane 5 : Whole cell lysate from NIH 3T3 cells at 50 µg


      Predicted band size : 109 kDa
      Observed band size : 109,117 kDa (why is the actual band size different from the predicted?)

    Anti-XRN2 antibody (ab72307)参考文献

    ab72307 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab72307.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"