Anti-XRCC2抗体[XRCC2 1G4/1] (ab20253)

概述

  • 产品名称Anti-XRCC2抗体[XRCC2 1G4/1]
    参阅全部 XRCC2 一抗
  • 描述
    小鼠单克隆抗体[XRCC2 1G4/1] to XRCC2
  • 特异性This antibody is specfic to XRCC2, and does not recognise other paralogs.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Hamster, Human
  • 免疫原

    Recombinant human denatured XRCC2 protein.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆单克隆
  • 克隆编号XRCC2 1G4/1
  • 骨髓瘤Sp2/0-Ag14
  • 同种型IgG1
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab20253 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 34 kDa.

靶标

  • 功能Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
  • 序列相似性Belongs to the RecA family. RAD51 subfamily.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp781P0919 antibody
    • DNA repair protein XRCC2 antibody
    • X ray repair complementing defective repair in Chinese hamster cells 2 antibody
    • X ray repair cross complementing protein 2 antibody
    • X-ray repair cross-complementing protein 2 antibody
    • Xrcc2 antibody
    • XRCC2_HUMAN antibody
    see all

Anti-XRCC2 antibody [XRCC2 1G4/1] (ab20253)参考文献

This product has been referenced in:
  • Xu K  et al. XRCC2 rs3218536 polymorphism decreases the sensitivity of colorectal cancer cells to poly(ADP-ribose) polymerase 1 inhibitor. Oncol Lett 8:1222-1228 (2014). WB ; Human . Read more (PubMed: 25120693) »
  • Gildemeister OS  et al. Cellular redistribution of Rad51 in response to DNA damage: novel role for Rad51C. J Biol Chem 284:31945-52 (2009). WB ; Human . Read more (PubMed: 19783859) »

See all 3 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"