RabMAb

Anti-XRCC2抗体[EPR5149] (ab124900)

概述

  • 产品名称Anti-XRCC2抗体[EPR5149]
    参阅全部 XRCC2 一抗
  • 描述
    兔单克隆抗体[EPR5149] to XRCC2
  • 经测试应用适用于: WB, Flow Cytmore details
    不适用于: ICC,IHC-P or IP
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to residues in Human XRCC2.

  • 阳性对照
    • Human testis, HeLa, SW480, SH-SY5Y, Caco 2 and Human kidney lysates.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

性能

应用

Our Abpromise guarantee covers the use of ab124900 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/10000 - 1/50000. Detects a band of approximately 34 kDa (predicted molecular weight: 32 kDa).
Flow Cyt 1/100 - 1/500. ab172730-Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • 应用说明Is unsuitable for ICC,IHC-P or IP.
  • 靶标

    • 功能Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
    • 序列相似性Belongs to the RecA family. RAD51 subfamily.
    • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • DKFZp781P0919 antibody
      • DNA repair protein XRCC2 antibody
      • X ray repair complementing defective repair in Chinese hamster cells 2 antibody
      • X ray repair cross complementing protein 2 antibody
      • X-ray repair cross-complementing protein 2 antibody
      • Xrcc2 antibody
      • XRCC2_HUMAN antibody
      see all

    Anti-XRCC2 antibody [EPR5149] 图像

    • All lanes : Anti-XRCC2 antibody [EPR5149] (ab124900) at 1/10000 dilution

      Lane 1 : Human testis lysate
      Lane 2 : HeLa lysate
      Lane 3 : SW480 lysate
      Lane 4 : SH-SY5Y lysate
      Lane 5 : Caco 2 lysate
      Lane 6 : Human kidney lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      Goat anti-Rabbit HRP at 1/2000 dilution

      Predicted band size : 32 kDa
    • ab124900 at 1/100 dilution staining XRCC2 in permeablised HeLa cells by Flow cytometry (red). Rabbit IgG negative control antibody (green).

    Anti-XRCC2 antibody [EPR5149] (ab124900)参考文献

    ab124900 has not yet been referenced specifically in any publications.

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