概述

  • 产品名称Anti-XRCC2抗体
    参阅全部 XRCC2 一抗
  • 描述
    兔多克隆抗体to XRCC2
  • 特异性ab58466 detects endogenous levels of total XRCC2 protein.
  • 经测试应用适用于: IHC-P, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from internal sequence of human XRCC2.

  • 阳性对照
    • IHC-P: Human lung carcinoma tissue.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明The antibody was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab58466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent concentration.
ELISA 1/10000.

靶标

  • 功能Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
  • 序列相似性Belongs to the RecA family. RAD51 subfamily.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp781P0919 antibody
    • DNA repair protein XRCC2 antibody
    • X ray repair complementing defective repair in Chinese hamster cells 2 antibody
    • X ray repair cross complementing protein 2 antibody
    • X-ray repair cross-complementing protein 2 antibody
    • Xrcc2 antibody
    • XRCC2_HUMAN antibody
    see all

Anti-XRCC2 antibody 图像

  • Ab58466, at 1/50 dilution, staining paraffin embedded human lung carcinoma tissue by Immunohistochemistry in the absence (left image) or presence (right image) of the immunising peptide.

Anti-XRCC2 antibody (ab58466)参考文献

ab58466 has not yet been referenced specifically in any publications.

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