参阅全部 XRCC1 一抗
- 特异性ab58465 detects endogenous levels of total XRCC1 protein.
WB, IHC-P, ELISAmore details
Synthetic peptide derived from internal sequence of human XRCC1.
- WB: Extracts from Jurkat cells.
IHC-P: human lung carcinoma tissue.
- 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- 存储溶液Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
Concentration information loading...
- 纯度Immunogen affinity purified
- 纯化说明The antibody was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||1/500 - 1/1000. Detects a band of approximately 70 kDa (predicted molecular weight: 70 kDa).
||Use at an assay dependent concentration.
- 功能Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents.
- 序列相似性Contains 2 BRCT domains.
- 翻译后修饰Phosphorylation of Ser-371 causes dimer dissociation. Phosphorylation by CK2 promotes interaction with APTX and APLF.
- 细胞定位Nucleus. Accumulates at sites of DNA damage.
Information by UniProt
- DNA repair protein XRCC1 antibody
- RCC antibody
- X ray repair complementing defective repair in chinese hamster antibody
Anti-XRCC1 antibody 图像
Western blot - XRCC1 antibody (ab58465)
All lanes : Anti-XRCC1 antibody (ab58465) at 1/500 dilution
Lane 1 : Extracts from Jurkat cells
Lane 2 : Extracts from Jurkat cells with immunizing peptide
Predicted band size : 70 kDa
Observed band size : 70 kDa
Immunohistochemistry (Paraffin-embedded sections) - XRCC1 antibody (ab58465)
Ab58465, at 1/50 dilution, staining paraffin embedded human lung carcinoma tissue by Immunohistochemistry in the absence (left image) or presence (right image) of the immunising peptide.
Anti-XRCC1 antibody (ab58465)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"