产品名称 Anti-xCT抗体 参阅全部 xCT 一抗
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Mouse, Dog, Pig, Orangutan
C-KGQTQNFKDAFSGRD , corresponding to internal sequence amino acids 215-229 of Human xCT
存放说明 Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
存储溶液 Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
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纯度 Immunogen affinity purified
纯化说明 Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.02 - 0.06 µg/ml. Detects a band of approximately 52 kDa (predicted molecular weight: 55 kDa).
功能 Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate.
序列相似性 Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
Information by UniProt
Amino acid transport system xc xCT antibody antibody
Amino acid transport system xc- antibody
Calcium channel blocker resistance protein CCBR1 antibody
Anti-xCT antibody (ab60171)参考文献
This product has been referenced in:
et al. Downregulation of Cystine Transporter x(c) by Irinotecan in human head and neck cancer FaDu xenografts. Chemotherapy 56:223-33 (2010).
Read more (PubMed: 20551639) »
et al. Extracellular thiol-assisted selenium uptake dependent on the x(c)- cystine transporter explains the cancer-specific cytotoxicity of selenite. Proc Natl Acad Sci U S A 106:11400-5 (2009).
Read more (PubMed: 19549867) »
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"