Anti-WWOX1 + 4抗体(ab14691)

概述

  • 产品名称Anti-WWOX1 + 4抗体
  • 描述
    兔多克隆抗体to WWOX1 + 4
  • 特异性Cross reacts with Wwox 1 and 4.
  • 经测试应用适用于: WB, ELISA, IHC-Frmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide, corresponding to C terminal amino acids 397-411 of Human WWOX1

性能

应用

Our Abpromise guarantee covers the use of ab14691 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent concentration. Predicted molecular weight: 46 kDa.
ELISA 1/10000.
IHC-Fr Use at an assay dependent concentration.

靶标

  • 相关性WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates 7 transcript variants, which encode different isoforms.
  • 细胞定位Cytoplasmic, Golgi Apparatus, Mitochondrial and Nuclear
  • 数据库链接
  • 别名
    • FRA16D antibody
    • fragile site FRA16D oxidoreductase antibody
    • putative oxidoreductase antibody
    • WW domain-containing oxidoreductase antibody
    • WWOX antibody
    see all

Anti-WWOX1 + 4 antibody (ab14691)参考文献

ab14691 has not yet been referenced specifically in any publications.

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1. Sie bekommen 100ug von diesem Antikörper. Bei einer Konzentration von 0.57mg/ml bedeutet das, dass Sie 175ul bekommen. <...

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