概述

  • 产品名称
    Anti-WRCH1抗体
    参阅全部 WRCH1 一抗
  • 描述
    兔多克隆抗体to WRCH1
  • 宿主
    Rabbit
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Recombinant fragment
    预测可用于: Mouse
  • 免疫原

    Synthetic peptide corresponding to N terminal residues of mouse WRCH1

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.01% Sodium Azide
    Constituents: 50% Glycerol, PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    Purified by antigen specific affinity chromatography.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab58617 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 28 kDa. This antibody has been tested in Western blot against the recombinant peptide used as an immunogen. We have no data on detection of endogenous protein.
ELISA Use at an assay dependent dilution.

靶标

  • 功能
    Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound.
  • 组织特异性
    Ubiquitously expressed in all tissues examined. Expressed at high levels in the stomach, small intestine, brain, skeletal muscle and placenta.
  • 序列相似性
    Belongs to the small GTPase superfamily. Rho family.
  • 细胞定位
    Cell membrane. Golgi apparatus membrane. Cell junction > focal adhesion. Cell projection > podosome. Localizes to podosomes in SRC-transformed cells.
  • Information by UniProt
  • 数据库链接
    • 别名
      • ARHU antibody
      • CDC42 L1 antibody
      • CDC42 like GTPase antibody
      • CDC42-like GTPase 1 antibody
      • CDC42L1 antibody
      • G28K antibody
      • GTP binding protein like 1 antibody
      • GTP binding protein SB128 antibody
      • GTP-binding protein-like 1 antibody
      • hG28K antibody
      • mG28K antibody
      • Ras homolog gene family member U antibody
      • Ras homolog gene family member U isoform CRA a antibody
      • Ras like gene family member U antibody
      • Rho GTPase like protein ARHU antibody
      • Rho GTPase-like protein ARHU antibody
      • Rho related GTP binding protein RhoU antibody
      • Rho-related GTP-binding protein RhoU antibody
      • Rhou antibody
      • RHOU_HUMAN antibody
      • Ryu GTPase antibody
      • Wnt-1 responsive Cdc42 homolog 1 antibody
      • Wnt1 responsive Cdc42 homolog antibody
      • WRCH 1 antibody
      • WRCH-1 antibody
      see all

    实验方案

    文献

    ab58617 has not yet been referenced specifically in any publications.

    发表研究结果有使用 ab58617？请让我们知道，以便我们可以引用本数据表中的参考文章。

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