Anti-Wnt3抗体[4F10-1D2] (ab52568)

概述

  • 产品名称Anti-Wnt3抗体[4F10-1D2]
    参阅全部 Wnt3 一抗
  • 描述
    小鼠单克隆抗体[4F10-1D2] to Wnt3
  • 特异性This antibody is specific for the mid region of the WNT3 protein. It does not react with WNTs 1, 2, 4, 5, and 6.
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Recombinant protein corresponding to an internal region of the human WNT3 protein

  • 阳性对照
    • WNT3 transfected 293 cells.

性能

应用

Our Abpromise guarantee covers the use of ab52568 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 40 kDa.
ELISA Use a concentration of 0.1 - 1 µg/ml.

靶标

  • 功能Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.
  • 疾病相关Defects in WNT3 are the cause of autosomal recessive tetra-amelia (ARTTRA) [MIM:273395]. Tetra-amelia is a rare human genetic disorder characterized by complete absence of all four limbs and other anomalies such as craniofacial, nervous system, pulmonary, skeletal and urogenital defects.
  • 序列相似性Belongs to the Wnt family.
  • 细胞定位Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Int 4 antibody
    • INT4 antibody
    • MGC131950 antibody
    • MGC138321 antibody
    • MGC138323 antibody
    • Proto-oncogene Int-4 homolog antibody
    • Proto-oncogene Wnt-3 antibody
    • wingless type MMTV integration site family member 3 antibody
    • Wnt 3 proto oncogene protein antibody
    • WNT 3 proto oncogene protein precursor antibody
    • wnt3 antibody
    • WNT3_HUMAN antibody
    see all

Anti-Wnt3 antibody [4F10-1D2] 图像

  • Anti-Wnt3 antibody [4F10-1D2] (ab52568) at 1 µg/ml + WNT3 transfected 293 cell lysate

    Predicted band size : 40 kDa
    Observed band size : 40 kDa

Anti-Wnt3 antibody [4F10-1D2] (ab52568)参考文献

ab52568 has not yet been referenced specifically in any publications.

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