概述

  • 产品名称Anti-WldS抗体
  • 描述
    兔多克隆抗体to WldS
  • 经测试应用适用于: WB, ICC/IF, IHC-P, IHC-Fr, IPmore details
  • 种属反应性
    与反应: Mouse
  • 免疫原

    Synthetic peptide:

    CDNIAVRGLHVGQHHQLLP

    (Mouse) conjugated to KLH

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: Whole serum
  • 纯度Whole antiserum
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab94345 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ICC/IF
IHC-P
IHC-Fr
IP
  • 应用说明ICC/IF: 1/2000 - 1/5000. Specificity is shown by a clear signal in WldS cells which is absent in wild-type cells (as wild-types lack WldS).
    IHC-P: 1/2000 - 1/5000. Specificity is shown by a clear signal in WldS cells which is absent in wild-type cells (as wild-types lack WldS).
    IHC-Fr: 1/2000 - 1/5000. Specificity is shown by a clear signal in WldS cells which is absent in wild-type cells (as wild-types lack WldS).
    IP: 1/20. See Laser, Conforti et al., 2006.
    WB: 1/2000 - 1/5000. A single band is seen at these dilutions. Predicted molecular weight: 43 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 相关性The slow Wallerian Degeneration (WldS) gene encodes a novel Ube4b-Nmnat1 chimeric protein (WldS protein). WldS protein confers a neuroprotective effect on axonal and synaptic compartments of neurons from a wide variety of degeneration-inducing stimuli. The chimeric WldS gene occurred as the result of a spontaneous mutation in C57BL/6 mice, resulting in a tandem triplication of a region already present on the distal region of chromosome 4. The triplicated region contains sequences coding for Nmnat1, Rbp7 and Ube4b. The boundaries within the triplicated region result in 2 copies of a fusion gene comprising the N70 terminal amino acids of Ube4b and the entire coding region of Nmnat1 (C Terminal 285 amino acids), linked by 18 amino acids from the 5' untranslated region of Nmnat1 which are not normally expressed.
    • 细胞定位Nuclear
    • 数据库链接
    • 别名
      • slow wallerian degeneration protein antibody
      • Wallerian degeneration protein antibody
      • Wld antibody

    Anti-WldS antibody 图像

    • All lanes : Anti-WldS antibody (ab94345) at 1/2000 dilution

      Lane 1 : Wild-type mouse brain homogenate
      Lane 2 : WldS mouse brain homogenate


      Predicted band size : 43 kDa
      Observed band size : 43 kDa

    Anti-WldS antibody (ab94345)参考文献

    ab94345 has not yet been referenced specifically in any publications.

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