Li N et al.AKT-mediated stabilization of histone methyltransferase WHSC1 promotes prostate cancer metastasis.J Clin Invest 127:1284-1302 (2017).
Hernando H et al.EZH2 Inhibition Blocks Multiple Myeloma Cell Growth through Upregulation of Epithelial Tumor Suppressor Genes.Mol Cancer Ther 15:287-98 (2016).
Evans DL et al.MMSET is dynamically regulated during cell-cycle progression and promotes normal DNA replication.Cell Cycle 15:95-105 (2016).
Saloura V et al.WHSC1 promotes oncogenesis through regulation of NIMA-related kinase-7 in squamous cell carcinoma of the head and neck.Mol Cancer Res 13:293-304 (2015).
WB, IP, IHC
Feng Q et al.An epigenomic approach to therapy for tamoxifen-resistant breast cancer.Cell Res 24:809-19 (2014).
Pei H et al.The histone methyltransferase MMSET regulates class switch recombination.J Immunol 190:756-63 (2013).
Hartlerode AJ et al.Impact of Histone H4 Lysine 20 Methylation on 53BP1 Responses to Chromosomal Double Strand Breaks.PLoS One 7:e49211 (2012).
Pei H et al.MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites.Nature 470:124-8 (2011).
Ram O et al.Combinatorial patterning of chromatin regulators uncovered by genome-wide location analysis in human cells.Cell 147:1628-39 (2011).