概述

  • 产品名称Anti-WHIP抗体
    参阅全部 WHIP 一抗
  • 描述
    兔多克隆抗体to WHIP
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Horse, Dog, Chimpanzee, Ferret, Rhesus monkey, Gorilla, Chinese Hamster, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region within residues 400 and 450 of human WHIP (NP_064520.2).

  • 阳性对照
    • Human controls: anaplastic thyroid carcinoma, breast carcinoma, colon carcinoma, linitis plastica stomach cancer, ovarian carcinoma, prostate carcinoma, stomach adenocarcinoma. Mouse controls: mouse teratoma.

性能

应用

Our Abpromise guarantee covers the use of ab84475 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500.
    Epitope exposure is recommended.
    Epitope exposure with citrate buffer will enhance staining.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Functions as a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. Has an intrinsic ATPase activity that functions as a sensor of DNA damage or of arrested replication forks and regulates the extent of DNA synthesis.
    • 组织特异性Ubiquitously expressed.
    • 序列相似性Belongs to the AAA ATPase family.
      Contains 1 UBZ-type zinc finger.
    • 翻译后修饰Sumoylated by SUMO1 and SUMO2/3.
    • 细胞定位Nucleus. Colocalizes with WRN in granular structures in the nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ATPase WRNIP 1 antibody
      • ATPase WRNIP1 antibody
      • bA420G6.2 antibody
      • FLJ22526 antibody
      • Putative helicase RUVBL antibody
      • RP11 420G6.2 antibody
      • Werner helicasae interacting protein 1 antibody
      • Werner helicasae interacting protein antibody
      • Werner helicase interacting protein isoform 2 antibody
      • Werner helicase-interacting protein 1 antibody
      • WRIP1_HUMAN antibody
      • WRNIP 1 antibody
      • WRNIP antibody
      • Wrnip1 antibody
      see all

    Anti-WHIP antibody 图像

    • ab84475, at a 1/250 dilution, staining WHIP in formalin fixed, paraffin embedded human breast carcinoma section by Immunohistochemistry .
      Detection: DAB staining.
    • ab84475, at a 1/250 dilution, staining WHIP in formalin fixed, paraffin embedded mouse teratoma section by Immunohistochemistry .
      Detection: DAB staining.

    Anti-WHIP antibody (ab84475)参考文献

    ab84475 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"