Anti-WRNIP1/WHIP抗体(ab18729)
Key features and details
- Goat polyclonal to WRNIP1/WHIP
- Suitable for: IHC-P, WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-WRNIP1/WHIP抗体
参阅全部 WRNIP1/WHIP 一抗 -
描述
山羊多克隆抗体to WRNIP1/WHIP -
宿主
Goat -
经测试应用
适用于: IHC-P, WBmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow, Dog -
免疫原
Synthetic peptide corresponding to Human WRNIP1/WHIP aa 652-665 (C terminal).
Sequence:EELRGVDFFKQRRC
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.30
Preservative: 0.02% Sodium azide
Constituent: 0.5% BSA -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab18729于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
Use a concentration of 4 - 6 µg/ml. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
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WB |
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 72 kDa.
1 hour primary incubation is recommended for this product. |
说明 |
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IHC-P
Use a concentration of 4 - 6 µg/ml. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol. |
WB
Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 72 kDa. 1 hour primary incubation is recommended for this product. |
靶标
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功能
Functions as a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. Has an intrinsic ATPase activity that functions as a sensor of DNA damage or of arrested replication forks and regulates the extent of DNA synthesis. -
组织特异性
Ubiquitously expressed. -
序列相似性
Belongs to the AAA ATPase family.
Contains 1 UBZ-type zinc finger. -
翻译后修饰
Sumoylated by SUMO1 and SUMO2/3. -
细胞定位
Nucleus. Colocalizes with WRN in granular structures in the nucleus. - Information by UniProt
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数据库链接
- Entrez Gene: 56897 Human
- Entrez Gene: 78903 Mouse
- Entrez Gene: 282835 Rat
- Omim: 608196 Human
- SwissProt: Q96S55 Human
- SwissProt: Q91XU0 Mouse
- SwissProt: Q8CG07 Rat
- Unigene: 236828 Human
see all -
别名
- ATPase WRNIP 1 antibody
- ATPase WRNIP1 antibody
- bA420G6.2 antibody
see all
图片
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ab18729 (4µg/ml) staining of paraffin embedded Human Kidney following steamed antigen retrieval with Tris/EDTA buffer pH 9 and HRP-staining shows nuclear staining, stronger in DCT compared to PCT.
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Anti-WRNIP1/WHIP antibody (ab18729) at 1 µg/ml + Jurkat Cell Lysate in RIPA Buffer at 35 µg
Developed using the ECL technique.
Predicted band size: 72 kDa
数据表及文件
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Datasheet download
文献 (0)
ab18729 尚未被引用在任何文献中。