概述

  • 产品名称Anti-WDR58抗体
    参阅全部 WDR58 一抗
  • 描述
    兔多克隆抗体to WDR58
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Horse, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 144-193 (AGGDCQLHTM DLETGTFTRV LRGHTDYIHC LALRERSPEV LSGGEDGAVR) of human WDR58 (NP_077315).

  • 阳性对照
    • Human fetal pancreas lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified by peptide affinity chromatography method.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab84900 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 38 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between THOC4 and the cap-binding protein NCBP1. DDX39B functions as a bridge between THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction between KSHV ORF57 protein and THOC4.
  • 序列相似性Belongs to the WD repeat THOC6 family.
    Contains 7 WD repeats.
  • Information by UniProt
  • 数据库链接
  • 别名
    • fSAP35 antibody
    • Functional spliceosome-associated protein 35 antibody
    • MGC2655 antibody
    • PSEC0006 antibody
    • THO complex 6 homolog antibody
    • THO complex subunit 6 homolog antibody
    • Thoc6 antibody
    • THOC6_HUMAN antibody
    • WD repeat containing protein 58 antibody
    • WD repeat domain 58 antibody
    • WD repeat-containing protein 58 antibody
    see all

Anti-WDR58 antibody 图像

  • Anti-WDR58 antibody (ab84900) at 1 µg/ml (in 5% skim milk / PBS buffer) + human fetal pancreas lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 38 kDa
    Observed band size : 38 kDa

Anti-WDR58 antibody (ab84900)参考文献

ab84900 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab84900.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"