Anti-WDR35抗体(ab105557)

概述

  • 产品名称Anti-WDR35抗体
    参阅全部 WDR35 一抗
  • 描述
    兔多克隆抗体to WDR35
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 71 - 120 (SGSVQVVTWN EQYQKLTTSD ENGLIIVWML YKGSWIEEMI NNRNKSVVRS) of Human WDR35 isoform 2 (NP_065830).

  • 阳性对照
    • Human fetal lung lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab105557 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 132 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能May promote CASP3 activation and TNF-stimulated apoptosis.
  • 疾病相关Defects in WDR35 are the cause of cranioectodermal dysplasia type 2 (CED2) [MIM:613610]. A disorder characterized by craniofacial, skeletal and ectodermal abnormalities. Clinical features include short stature, dolichocephaly, craniosynostosis, narrow thorax with pectus excavatum, short limbs, brachydactyly, joint laxity, narrow palpebral fissures, telecanthus with hypertelorism, low-set simple ears, everted lower lip, and short neck. Teeth abnormalities included widely spaced, hypoplastic and fused teeth.
  • 序列相似性Contains 5 WD repeats.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Intraflagellar transport protein 121 homolog antibody
    • KIAA1336 antibody
    • MGC33196 antibody
    • Naofen antibody
    • WD repeat domain 35 antibody
    • WD repeat-containing protein 35 antibody
    • WDR35 antibody
    • WDR35_HUMAN antibody
    see all

Anti-WDR35 antibody 图像

  • Anti-WDR35 antibody (ab105557) at 1 µg/ml + Human fetal lung lysate at 10 µg

    Predicted band size : 132 kDa

Anti-WDR35 antibody (ab105557)参考文献

ab105557 has not yet been referenced specifically in any publications.

Product Wall

Abreviews
Application Western blot
Loading amount 40 µg
Gel Running Conditions Reduced Denaturing (8% acrylamide/bis)
Sample Mouse Cell lysate - whole cell (Mouse embryonic fibroblasts)
Specification Mouse embryonic fibroblasts
Blocking step Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 21°C
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提交于 Apr 04 2014

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"