Anti-VTA1抗体(ab96738)
Key features and details
- Rabbit polyclonal to VTA1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-VTA1抗体 -
描述
兔多克隆抗体to VTA1 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat, Cow -
免疫原
Recombinant fragment, corresponding to a sequence within amino acids 1-246 of Human VTA1
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阳性对照
- H1299, HeLaS3, Molt4 whole cell lysates; SW480 xenograft tissue.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab96738于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 34 kDa.
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IHC-P |
1/100 - 1/500.
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说明 |
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WB
1/500 - 1/3000. Predicted molecular weight: 34 kDa. |
IHC-P
1/100 - 1/500. |
靶标
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功能
Involved in the endosomal multivesicular bodies (MVB) pathway. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. Thought to be a cofactor of VPS4A/B, which catalyzes disassembles membrane-associated ESCRT-III assemblies. Involved in the sorting and down-regulation of EGFR (By similarity). Involved in HIV-1 budding. -
序列相似性
Belongs to the VTA1 family. -
细胞定位
Cytoplasm. Endosome membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 506430 Cow
- Entrez Gene: 51534 Human
- Entrez Gene: 66201 Mouse
- Entrez Gene: 292640 Rat
- Omim: 610902 Human
- SwissProt: Q32L63 Cow
- SwissProt: Q9NP79 Human
- SwissProt: Q9CR26 Mouse
see all -
别名
- C6orf55 antibody
- Chromosome 6 open reading frame 55 antibody
- Dopamine responsive protein DRG 1 antibody
see all
图片
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All lanes : Anti-VTA1 antibody (ab96738) at 1/1000 dilution
Lane 1 : H1299 whole cell lysate
Lane 2 : HeLaS3 whole cell lysate
Lane 3 : Molt4 whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 34 kDa
12% SDS-PAGE. -
ab96738 at 1/500 dilution staining VTA1 in SW480 xenograft by Immunohistochemistry, Paraffin-embedded tissue.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab96738 尚未被引用在任何文献中。