Anti-VRL1抗体(ab6182)

概述

  • 产品名称Anti-VRL1抗体
    参阅全部 VRL1 一抗
  • 描述
    兔多克隆抗体to VRL1
  • 特异性Immunohistochemical analysis of rat dorsal root ganglia and spinal cord indicates high level of specificity for this antiserum. Cross reactivity: This antibody is known to react with rat. Other species have not been tested yet.
  • 经测试应用适用于: IHC-Frmore details
  • 种属反应性
    与反应: Rat
  • 免疫原

    Synthetic peptide: C(744)KNSASEEDHLPLQVLQSP(761) (Rat) conjugated to KLH by a Glutaraldehyde linker.

  • 常规说明This antibody is excellent for immunohistochemistry. It stains a subpopulation of neurons in the rat dorsal root ganglia. VRL 1 is also known as Vanilloid Receptor Like protein-1.

性能

应用

Our Abpromise guarantee covers the use of ab6182 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr
  • 应用说明Immunohistochemistry: 1/2,000
    Western Blot: Not tested.
    Immunoblot: Not tested.
    1 site ELISA: Not tested.
    Biological Inhibition: Not tested.
  • 靶标

    • 功能Calcium-permeable, non-selective cation channel with an outward rectification. Seems to be regulated, at least in part, by IGF-I, PDGF and neuropeptide head activator. May transduce physical stimuli in mast cells. Activated by temperatures higher than 52 degrees Celsius; is not activated by vanilloids and acidic pH.
    • 序列相似性Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV2 sub-subfamily.
      Contains 6 ANK repeats.
    • 翻译后修饰N-glycosylated.
      Phosphorylated by PKA.
    • 细胞定位Cell membrane. Cytoplasm. Melanosome. Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
    • Information by UniProt
    • 数据库链接
    • 别名
      • MGC12549 antibody
      • Osm 9 like TRP channel 2 antibody
      • Osm-9-like TRP channel 2 antibody
      • OTRPC2 antibody
      • Sac2b antibody
      • Stretch activated channel 2B antibody
      • Transient receptor potential cation channel subfamily V member 2 antibody
      • TRPV2 antibody
      • TRPV2_HUMAN antibody
      • Vanilloid receptor like protein 1 antibody
      • Vanilloid receptor-like protein 1 antibody
      • VRL 1 antibody
      • VRL antibody
      • VRL-1 antibody
      • VRL1 antibody
      see all

    Anti-VRL1 antibody (ab6182)参考文献

    ab6182 has not yet been referenced specifically in any publications.

    Product Wall

    Thank you for your phone call and I apologize for the damaged antibody that you received. The free of charge replacement vial is being sent to your attention on order reference # 99608 and you should receive this tomorrow. Please let me know if y...

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