Anti-VPS37D抗体(ab122683)
Key features and details
- Rabbit polyclonal to VPS37D
- Suitable for: IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-VPS37D抗体 -
描述
兔多克隆抗体to VPS37D -
宿主
Rabbit -
经测试应用
适用于: IHC-P, ICC/IFmore details -
种属反应性
与反应: Human -
免疫原
antigen sequence: LRDLLQDEPK LDRIVRLSRK FQGLQLEREA CLASNYALAK ENLALRPRLE MGRAALAIKY QELREVAENC ADKLQRLEES MHRWSPHC, corresponding to amino acids 27-114 of Human VPS37D.
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阳性对照
- IHC: Human liver tissue. ICC/IF: Human cell line SH-SY5Y.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab122683于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-P |
1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
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说明 |
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IHC-P
1/20 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ICC/IF
Use a concentration of 0.25 - 2 µg/ml. |
靶标
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功能
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. -
疾病相关
Note=VPS37D is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. -
序列相似性
Belongs to the VPS37 family.
Contains 1 VPS37 C-terminal domain. -
细胞定位
Late endosome membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 155382 Human
- Omim: 610039 Human
- SwissProt: Q86XT2 Human
- Unigene: 647037 Human
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别名
- ESCRT-I complex subunit VPS37D antibody
- MGC35352 antibody
- Vacuolar protein sorting-associated protein 37D antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab122683 尚未被引用在任何文献中。