The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.03 - 0.1 µg/ml. Predicted molecular weight: 39 kDa.
Use a concentration of 3 - 6 µg/ml.
功能Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
序列相似性Belongs to the VPS37 family. Contains 1 VPS37 C-terminal domain.
细胞定位Late endosome membrane. Probably associates with membranes. Recruited to the plasma membrane by HIV-1.