概述

  • 产品名称Anti-VPS29抗体
    参阅全部 VPS29 一抗
  • 描述
    兔多克隆抗体to VPS29
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Drosophila melanogaster, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 35-84 (LCTGNLCTKE SYDYLKTLAG DVHIVRGDFD ENLNYPEQKV VTVGQFKIGL) of Human VPS29 (NP_057310).

  • 阳性对照
    • ACHN cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab98929 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 21 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro).
  • 组织特异性Ubiquitous. Highly expressed in heart, lung, placenta, spleen, peripheral blood leukocytes, thymus, colon skeletal muscle, kidney and brain.
  • 序列相似性Belongs to the VPS29 family.
  • 细胞定位Cytoplasm. Membrane. Endosome membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DC15 antibody
    • DC7 antibody
    • DKFZp564F0223 antibody
    • FLJ20492 antibody
    • hVPS29 antibody
    • PEP11 antibody
    • PEP11 homolog antibody
    • Retromer protein antibody
    • Vacuolar protein sorting 29 antibody
    • Vacuolar protein sorting 29 (yeast homolog) antibody
    • Vacuolar protein sorting 29 (yeast) antibody
    • Vacuolar protein sorting 29 homolog (S. cerevisiae) antibody
    • Vacuolar protein sorting 29 homolog antibody
    • Vacuolar protein sorting associated protein 29 antibody
    • Vacuolar protein sorting-associated protein 29 antibody
    • Vacuolar sorting protein VPS29/PEP11 antibody
    • Vesicle protein sorting 29 antibody
    • VPS 29 antibody
    • VPS29 antibody
    • VPS29_HUMAN antibody
    • x 007 protein antibody
    see all

Anti-VPS29 antibody 图像

  • Anti-VPS29 antibody (ab98929) at 1 µg/ml + ACHN cell lysate at 10 µg

    Predicted band size : 21 kDa

Anti-VPS29 antibody (ab98929)参考文献

This product has been referenced in:
  • Munsie LN  et al. Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N. Hum Mol Genet 24:1691-703 (2015). Read more (PubMed: 25416282) »
  • Fuse A  et al. VPS29-VPS35 intermediate of retromer is stable and may be involved in the retromer complex assembly process. FEBS Lett 589:1430-6 (2015). Read more (PubMed: 25937119) »

See all 2 Publications for this product

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