概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Human
    • 序列C-QPNVDTRQKQ
    • 氨基酸20 to 29

相关产品

技术指标

Our Abpromise guarantee covers the use of ab45840 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-VPS25 antibody (ab42500)

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.

常规信息

  • 别名
    • Dermal papilla derived protein 9
    • Dermal papilla-derived protein 9
    • DERP9
    • EAP20
    • ELL associated protein of 20 kDa
    • ELL-associated protein of 20 kDa
    • ESCRT-II complex subunit VPS25
    • FAP20
    • HGNC:28122
    • hVps25
    • MGC10540
    • Vacuolar protein sorting 25 homolog (S. cerevisiae)
    • Vacuolar protein sorting associated protein 25
    • Vacuolar protein-sorting-associated protein 25
    • VPS25
    • VPS25_HUMAN
    see all
  • 功能Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation, possibly via its interaction with ELL. The ESCRT-II complex may be involved in facilitating the budding of certain RNA viruses.
  • 组织特异性Expressed at the mRNA level in kidney, liver, pancreas, and placenta. Lower levels of expression are found in heart, skeletal muscle, brain and lung.
  • 序列相似性Belongs to the VPS25 family.
  • 细胞定位Cytoplasm. Endosome membrane. Nucleus > nucleoplasm. Distributes diffusely throughout the cytoplasm and nucleoplasm, but exhibits a punctate distribution on coexpression with CHMP6.
  • Information by UniProt

VPS25 peptide (20-29) (ab45840)参考文献

ab45840 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab45840.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"