Anti-VNN1/Vanin-1抗体(ab96171)
Key features and details
- Rabbit polyclonal to VNN1/Vanin-1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
-
产品名称
Anti-VNN1/Vanin-1抗体
参阅全部 VNN1/Vanin-1 一抗 -
描述
兔多克隆抗体to VNN1/Vanin-1 -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human -
免疫原
Recombinant fragment corresponding to Human VNN1/Vanin-1 aa 232-427 (internal sequence).
-
阳性对照
- H1299, HeLa or HepG2 cell lines.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
存储溶液
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
-
纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
-
Compatible Secondaries
-
Isotype control
-
Positive Controls
-
Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab96171于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
WB |
1/500 - 1/3000. Predicted molecular weight: 57 kDa.
|
说明 |
---|
WB
1/500 - 1/3000. Predicted molecular weight: 57 kDa. |
靶标
-
功能
Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. -
组织特异性
Widely expressed with higher expression in spleen, kidney and blood. Overexpressed in lesional psoriatic skin. -
序列相似性
Belongs to the CN hydrolase family. BTD/VNN subfamily.
Contains 1 CN hydrolase domain. -
细胞定位
Cell membrane. - Information by UniProt
-
数据库链接
- Entrez Gene: 8876 Human
- Omim: 603570 Human
- SwissProt: O95497 Human
- Unigene: 12114 Human
- Unigene: 720659 Human
-
别名
- HDLCQ8 antibody
- High density lipoprotein cholesterol level quantitative trait locus 8, included antibody
- Pantetheinase antibody
see all
图片
数据表及文件
-
SDS download
-
Datasheet download
文献 (1)
ab96171 被引用在 1 文献中.
- Povero D et al. Lipid-induced toxicity stimulates hepatocytes to release angiogenic microparticles that require Vanin-1 for uptake by endothelial cells. Sci Signal 6:ra88 (2013). Neutralising ; Human . PubMed: 24106341