Anti-Vitamin B9 / Folic acid抗体[B762F] (ab38244)

概述

• 产品名称Anti-Vitamin B9 / Folic acid抗体[B762F]
• 描述
  小鼠单克隆抗体[B762F] to Vitamin B9 / Folic acid
• 特异性This antibody reacts with free folic acid.
• 经测试应用适用于: ELISAmore details
• 免疫原

  Chemical/ Small Molecule, Folic acid conjugated to BSA

性能

• 形式Liquid
• 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
• 存储溶液Preservative: 0.1% Sodium Azide
  Constituents: PBS, pH 7.4
• Concentration information loading...
• 纯度Protein G purified
• 纯化说明>95% pure. Purity was tested by electrophoresis.
• 克隆单克隆
• 克隆编号B762F
• 骨髓瘤Sp2/0
• 同种型IgG1
• 研究领域
  • Signal Transduction
  • Metabolism
  • Vitamins / Minerals

  • Metabolism
  • Pathways and Processes
  • Cofactors, Vitamins / minerals
  • Vitamins / minerals

  • Metabolism
  • Types of disease
  • Cancer

相关产品

• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

应用

靶标

• 相关性Folic acid and Folate (the anion form) are forms of a water-soluble B vitamin. These occur naturally in food and can also be taken as supplements. The biologically active form of folic acid is tetrahydrofolic acid (THFA), which is derived by the 2-step reduction of folate involving dihydrofolate reductase. THFA plays a key role in the transfer of 1-carbon units (such as methyl, methylene, and formyl groups) to the essential substrates involved in the synthesis of DNA, RNA, and proteins. More specifically, THFA is involved with the enzymatic reactions necessary to synthesis of purines, thymidine, and amino acids. Manifestations of folate deficiency thereafter, not surprisingly, would involve impairment of cell division, accumulation of possibly toxic metabolites such as homocysteine, and impairment of methylation reactions involved in the regulation of gene expression, thus increasing neoplastic risks. Folate is necessary for the production and maintenance of new cells. This is especially important during periods of rapid cell division and growth such as infancy and pregnancy when a deficiency can result in neural tube defects. In folate deficiency the bone marrow is affected as it is a site of rapid cell turnover. Large red blood cells called megaloblasts are produced, resulting in megaloblastic anemia.
• 别名
  • 5 Methyl THFA antibody
  • 5 Methyltetrahydrofolate antibody
  • Folate antibody

  • Tetrahydrofolate antibody
  • Tetrahydrofolic acid antibody
  • THFA antibody

  see all