Anti-Vitamin B9 / Folic acid抗体[B762F] (ab38244)

概述

  • 产品名称Anti-Vitamin B9 / Folic acid抗体[B762F]
  • 描述
    小鼠单克隆抗体[B762F] to Vitamin B9 / Folic acid
  • 特异性This antibody reacts with free folic acid.
  • 经测试应用适用于: ELISAmore details
  • 免疫原

    Chemical/ Small Molecule, Folic acid conjugated to BSA

性能

应用

Our Abpromise guarantee covers the use of ab38244 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent dilution.

靶标

  • 相关性Folic acid and Folate (the anion form) are forms of a water-soluble B vitamin. These occur naturally in food and can also be taken as supplements. The biologically active form of folic acid is tetrahydrofolic acid (THFA), which is derived by the 2-step reduction of folate involving dihydrofolate reductase. THFA plays a key role in the transfer of 1-carbon units (such as methyl, methylene, and formyl groups) to the essential substrates involved in the synthesis of DNA, RNA, and proteins. More specifically, THFA is involved with the enzymatic reactions necessary to synthesis of purines, thymidine, and amino acids. Manifestations of folate deficiency thereafter, not surprisingly, would involve impairment of cell division, accumulation of possibly toxic metabolites such as homocysteine, and impairment of methylation reactions involved in the regulation of gene expression, thus increasing neoplastic risks. Folate is necessary for the production and maintenance of new cells. This is especially important during periods of rapid cell division and growth such as infancy and pregnancy when a deficiency can result in neural tube defects. In folate deficiency the bone marrow is affected as it is a site of rapid cell turnover. Large red blood cells called megaloblasts are produced, resulting in megaloblastic anemia.
  • 别名
    • 5 Methyl THFA antibody
    • 5 Methyltetrahydrofolate antibody
    • Folate antibody
    • Tetrahydrofolate antibody
    • Tetrahydrofolic acid antibody
    • THFA antibody
    see all

Anti-Vitamin B9 / Folic acid antibody [B762F] (ab38244)参考文献

ab38244 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab38244.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"