概述

  • 产品名称Anti-Viperin抗体
    参阅全部 Viperin 一抗
  • 描述
    兔多克隆抗体to Viperin
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
    预测可用于: Rabbit, Horse, Chicken, Turkey, Pig, Chimpanzee, Rhesus monkey, Opossum, Chinese Hamster, Orangutan, Zebra finch, Loxodonta Africana (African bush elephant)
  • 免疫原

    Synthetic peptide, corresponding to a region within amino acids 165-215 of Human Viperin (NP_542388.2).

  • 阳性对照
    • Human brain, Mouse brain and Rat brain lysates, Human rectum tissue

性能

应用

Our Abpromise guarantee covers the use of ab121042 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 3 - 5 µg/ml. Predicted molecular weight: 42 kDa.
IHC-P Use a concentration of 5 µg/ml.

靶标

  • 功能Involved in antiviral defense. May impair virus budding by disrupting lipid rafts at the plasma membrane, a feature which is essential for the budding process of many viruses. Acts through binding with and inactivating FPPS, an enzyme involved in synthesis of cholesterol, farnesylated and geranylated proteins, ubiquinones dolichol and heme. Plays a major role in the cell antiviral state induced by type I and type II interferon. Displays antiviral effect against HIV-1 virus, hepatitis C virus, human cytomegalovirus, and aphaviruses, but not vesiculovirus.
  • 序列相似性Belongs to the RSAD2 family.
  • 细胞定位Endoplasmic reticulum membrane. Golgi apparatus. Probably associates with the cytosolic side of the endoplasmic reticulum. Infection with human cytomegalovirus (HCMV) causes relocation to the Golgi apparatus and to cytoplasmic vacuoles which also contain HCMV proteins glycoprotein B and pp28.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 2510004L01Rik antibody
    • cig 33 antibody
    • CIG 5 antibody
    • cig-33 antibody
    • CIG-5 antibody
    • CIG33 antibody
    • CIG5 antibody
    • Cytomegalovirus induced gene 5 protein antibody
    • Cytomegalovirus-induced gene 5 protein antibody
    • endoplasmic reticulum-associated antibody
    • interferon-inducible antibody
    • Radical S adenosyl methionine domain containing 2 antibody
    • Radical S-adenosyl methionine domain-containing protein 2 antibody
    • RSAD 2 antibody
    • Rsad2 antibody
    • RSAD2_HUMAN antibody
    • RSDA-2 antibody
    • VIG 1 antibody
    • vig1 antibody
    • Viperin antibody
    • Virus inhibitory protein antibody
    • virus inhibitory protein endoplasmic reticulum associated interferon inducible antibody
    see all

Anti-Viperin antibody 图像

  • All lanes : Anti-Viperin antibody (ab121042) at 3 µg/ml

    Lane 1 : Human brain lysate
    Lane 2 : Human brain lysate with immunizing peptide
    Lane 3 : Mouse brain lysate
    Lane 4 : Rat brain lysate

    Lysates/proteins at 40 µg per lane.

    Secondary
    goat anti-rabbit I HRP
    Developed using the ECL technique

    Predicted band size : 42 kDa
  • Human rectum tissue probed with ab121042 at a concentration of 5 ug/ml.

Anti-Viperin antibody (ab121042)参考文献

This product has been referenced in:
  • Tateda K  et al. The suppression of TRIM21 and the accumulation of IFN-a play crucial roles in the pathogenesis of osteonecrosis of the femoral head. Lab Invest 92:1318-29 (2012). Rat . Read more (PubMed: 22825687) »

See 1 Publication for this product

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