Anti-VIP抗体(ab8556)
Key features and details
- Rabbit polyclonal to VIP
- Suitable for: IHC-P, IP, IHC-FoFr, WB, ICC
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-VIP抗体
参阅全部 VIP 一抗 -
描述
兔多克隆抗体to VIP -
宿主
Rabbit -
特异性
This antibody reacts with a 3 kD vasointestinal peptide (VIP) localized in nerve fibers in the central and peripheral nervous system. The VIP producing tumors are usually neuroblastomas of endocrine tumors in the pancreas. -
经测试应用
适用于: IHC-P, IP, IHC-FoFr, WB, ICCmore details -
种属反应性
与反应: Mouse, Rat, Human -
免疫原
Full length protein corresponding to Human VIP.
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常规说明
This antibody detects ganglion cells in both the superficial and deep plexus of the wall of the small bowel in human.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
存储溶液
pH: 7.40
Preservative: 0.1% Sodium azide
Constituent: 0.01% PBS -
Concentration information loading...
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纯度
Protein G purified -
纯化说明
After solid-phase absorption this antibody is filtered through a 0.22 µm filter, vialed and lyophilized. -
Primary antibody说明
This antibody detects ganglion cells in both the superficial and deep plexus of the wall of the small bowel in human. -
克隆
多克隆 -
同种型
IgG -
轻链类型
unknown -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
应用 | Ab评论 | 说明 |
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IHC-P |
Use at an assay dependent concentration.
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IP |
Use at an assay dependent concentration.
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IHC-FoFr |
Use at an assay dependent concentration. PubMed: 29751824
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 19 kDa.
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|
ICC |
Use at an assay dependent concentration.
|
说明 |
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IHC-P
Use at an assay dependent concentration. |
IP
Use at an assay dependent concentration. |
IHC-FoFr
Use at an assay dependent concentration. PubMed: 29751824 |
WB
Use at an assay dependent concentration. Predicted molecular weight: 19 kDa. |
ICC
Use at an assay dependent concentration. |
靶标
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功能
VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.
PHM and PHV also cause vasodilation. -
序列相似性
Belongs to the glucagon family. -
细胞定位
Secreted. - Information by UniProt
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数据库链接
- Entrez Gene: 7432 Human
- Entrez Gene: 22353 Mouse
- Entrez Gene: 117064 Rat
- Omim: 192320 Human
- SwissProt: P01282 Human
- SwissProt: P32648 Mouse
- SwissProt: P01283 Rat
- Unigene: 53973 Human
see all -
别名
- Peptide histidine methioninamide 27 antibody
- Peptide histidine valine 42 antibody
- PHM27 antibody
see all
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (12)
ab8556 被引用在 12 文献中.
- Erendor F et al. Lentiviral gene therapy vectors encoding VIP suppressed diabetes-related inflammation and augmented pancreatic beta-cell proliferation. Gene Ther 28:130-141 (2021). PubMed: 32733091
- Cheng CY et al. Membrane metalloendopeptidase suppresses prostate carcinogenesis by attenuating effects of gastrin-releasing peptide on stem/progenitor cells. Oncogenesis 9:38 (2020). PubMed: 32205838
- Li S et al. VIP activates primordial follicles of rat through ERK-mTOR pathway during in tissue culture. Reproduction N/A:N/A (2019). PubMed: 30817320
- Maiti AK et al. Colonic levels of vasoactive intestinal peptide decrease during infection and exogenous VIP protects epithelial mitochondria against the negative effects of IFN? and TNFa induced during Citrobacter rodentium infection. PLoS One 13:e0204567 (2018). PubMed: 30252907
- Valadas JS et al. ER Lipid Defects in Neuropeptidergic Neurons Impair Sleep Patterns in Parkinson's Disease. Neuron 98:1155-1169.e6 (2018). PubMed: 29887339