Anti-VGLUT3抗体[3D11] (ab81870)

概述

  • 产品名称Anti-VGLUT3抗体[3D11]
    参阅全部 VGLUT3 一抗
  • 描述
    小鼠单克隆抗体[3D11] to VGLUT3
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein (Human)

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Preservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆单克隆
  • 克隆编号3D11
  • 同种型IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab81870 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Predicted molecular weight: 65 kDa.
ELISA Use at an assay dependent dilution.

靶标

  • 功能Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate.
  • 组织特异性Expressed in amygdala, cerebellum, hippocampus, medulla, spinal cord and thalamus.
  • 疾病相关Defects in SLC17A8 are the cause of deafness autosomal dominant type 25 (DFNA25) [MIM:605583]. DFNA25 is a form of sensorineural hearing loss. The expression of DFNA25 deafness is variable in terms of onset and rate of progression, with an age-dependent penetrance resembling an early-onset presbycusis, or senile deafness, a progressive bilateral loss of hearing that occurs in the aged.
  • 序列相似性Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.
  • 细胞定位Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Membrane. Cell junction > synapse > synaptosome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • deafness autosomal dominant 25 antibody
    • DFNA 25 antibody
    • DFNA25 antibody
    • SLC17A8 antibody
    • Solute carrier family 17 (sodium dependent inorganic phosphate cotransporter) member 8 antibody
    • Solute carrier family 17 member 8 antibody
    • Vesicular glutamate transporter 3 antibody
    • VGLU3_HUMAN antibody
    • VGLUT 3 antibody
    • VGluT3 antibody
    see all

Anti-VGLUT3 antibody [3D11] (ab81870)参考文献

ab81870 has not yet been referenced specifically in any publications.

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