概述

  • 产品名称Anti-VEGFR 1+VEGFR 2抗体
  • 描述
    兔多克隆抗体to VEGFR 1+VEGFR 2
  • 特异性This antibody is specific for VEGFR 1 with significant cross-reactivity with the VEGFR 2 protein.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to Mouse VEGFR 1+VEGFR 2 aa 800-900.
    Sequence:

    PDEVPLDEQCERLPYDASKWEFARERLKLGKSLGRGAFGK VVQASAFG IKKSPTCRTVAVKMLKEGATASEYKALMTELKILTHIGHHLNVVNLLGAC TK

  • 阳性对照
    • HUVEC lysate

应用

Our Abpromise guarantee covers the use of ab36844 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/250 - 1/1000. Predicted molecular weight: 150 kDa.

靶标

  • 相关性Receptors for VEGF, VEGFB and PGF have a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, are thought to be important for the development of embryonic vasculature. It has been shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity, playing an inhibitory role in angiogenesis.
  • 细胞定位Cell Membrane
  • 数据库链接
  • 别名
    • FLK1 antibody
    • FLT1 antibody
    • KDR antibody
    • Kinase insert domain receptor antibody
    • Vascular endothelial growth factor receptor 1 antibody
    • Vascular endothelial growth factor receptor 2 antibody
    • Vascular permeability factor receptor antibody
    • VEGFR antibody
    • VEGFR1 antibody
    see all

Anti-VEGFR 1+VEGFR 2 antibody (ab36844)参考文献

This product has been referenced in:
  • Nusrat O  et al. The Role of Angiogenesis in the Persistence of Chemoresistance in Epithelial Ovarian Cancer. Reprod Sci 23:1484-1492 (2016). Read more (PubMed: 27122375) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"