Anti-VEGFR 1+VEGFR 2抗体(ab36844)

概述

• 产品名称
  Anti-VEGFR 1+VEGFR 2抗体
• 描述
  兔多克隆抗体to VEGFR 1+VEGFR 2
• 特异性
  This antibody is specific for VEGFR 1 with significant cross-reactivity with the VEGFR 2 protein.
• 经测试应用
  适用于: WBmore details
• 种属反应性
  与反应: Mouse, Human
  
• 免疫原

  Synthetic peptide corresponding to Mouse VEGFR 1+VEGFR 2 aa 800-900.
  Sequence:

  PDEVPLDEQCERLPYDASKWEFARERLKLGKSLGRGAFGK VVQASAFG IKKSPTCRTVAVKMLKEGATASEYKALMTELKILTHIGHHLNVVNLLGAC TK

  Run BLAST with Run BLAST with
• 阳性对照
  • HUVEC lysate

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• 存储溶液
  Preservative: 0.05% Sodium Azide
  
• Concentration information loading...
• 纯度
  Protein A purified
• 纯化说明
  ab36844 is an affinity purified IgG.
• 克隆
  多克隆
• 同种型
  IgG
• 研究领域
  • Cardiovascular
  • Angiogenesis
  • Growth Factors
  • VEGF
  • VEGF Receptors

  • Signal Transduction
  • Protein Phosphorylation
  • Tyrosine Kinases
  • Src Family

  • Signal Transduction
  • Protein Phosphorylation
  • Tyrosine Kinases
  • Receptor Tyrosine Kinases

  • Signal Transduction
  • Growth Factors/Hormones
  • VEGF

  • Cancer
  • Growth factors
  • VEGF

  • Cancer
  • Invasion/microenvironment
  • Angiogenesis
  • Angiogenic growth factors

  • Cancer
  • Oncoproteins/suppressors
  • Oncoproteins
  • Growth factor receptors

  • Cancer
  • Cancer Metabolism
  • Response to hypoxia

  • Metabolism
  • Pathways and Processes
  • Metabolism processes
  • Hypoxia

  • Metabolism
  • Types of disease
  • Cancer

  • Cardiovascular
  • Angiogenesis
  • Endothelial Cell Markers

相关产品

• Compatible Secondaries
  • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
  • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)

应用

靶标

• 相关性
  Receptors for VEGF, VEGFB and PGF have a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, are thought to be important for the development of embryonic vasculature. It has been shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity, playing an inhibitory role in angiogenesis.
• 细胞定位
  Cell Membrane
• 数据库链接
  • Entrez Gene: 2321 Human
  • Entrez Gene: 3791 Human
  • Entrez Gene: 14254 Mouse
  • Entrez Gene: 16542 Mouse
  • Omim: 165070 Human
  • Omim: 191306 Human
  • SwissProt: P17948 Human
  • SwissProt: P35968 Human

  • SwissProt: P35918 Mouse
  • SwissProt: P35969 Mouse
  • Unigene: 479756 Human
  • Unigene: 654360 Human

  see all
• 别名
  • FLK1 antibody
  • FLT1 antibody
  • KDR antibody

  • Kinase insert domain receptor antibody
  • Vascular endothelial growth factor receptor 1 antibody
  • Vascular endothelial growth factor receptor 2 antibody
  • Vascular permeability factor receptor antibody
  • VEGFR antibody
  • VEGFR1 antibody

  see all

实验方案

• Western blot protocols