Anti-VEGFD抗体(ab63068)

概述

  • 产品名称Anti-VEGFD抗体
    参阅全部 VEGFD 一抗
  • 描述
    兔多克隆抗体to VEGFD
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    KLH conjugated synthetic peptide selected from the C-terminal region of human VEGFD.

  • 阳性对照
    • 293 cell lysate; human lung carcinoma tissue.

性能

应用

Our Abpromise guarantee covers the use of ab63068 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/250 - 1/500. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa).
ELISA 1/1000.
IHC-P 1/50 - 1/100.

靶标

  • 功能Growth factor active in angiogenesis, lymphangiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the permeability of blood vessels. May function in the formation of the venous and lymphatic vascular systems during embryogenesis, and also in the maintenance of differentiated lymphatic endothelium in adults. Binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors.
  • 组织特异性Highly expressed in lung, heart, small intestine and fetal lung, and at lower levels in skeletal muscle, colon, and pancreas.
  • 序列相似性Belongs to the PDGF/VEGF growth factor family.
  • 翻译后修饰Undergoes a complex proteolytic maturation which generates a variety of processed secreted forms with increased activity toward VEGFR-3 and VEGFR-2. VEGF-D first form an antiparallel homodimer linked by disulfide bonds before secretion. The fully processed VEGF-D is composed mostly of two VEGF homology domains (VHDs) bound by non-covalent interactions.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • c-fos induced growth factor antibody
    • c-fos induced growth factor (vascular endothelial growth factor D) antibody
    • c-fos induced growth factor antibody
    • c-fos-induced growth factor antibody
    • FIGF antibody
    • Vascular endothelial growth factor D antibody
    • Vascular endothelial growth factor D precursor antibody
    • Vascular endothelial growth factor D precursor antibody
    • VEGF D antibody
    • VEGF-D antibody
    • VEGFD antibody
    • VEGFD_HUMAN antibody
    see all

Anti-VEGFD antibody 图像

  • Anti-VEGFD antibody (ab63068) at 1/250 dilution + 293 cell lysate at 12.5 µg

    Predicted band size : 40 kDa
    Observed band size : 40 kDa
    Additional bands at : 72 kDa. We are unsure as to the identity of these extra bands.
  • Ab63068 (1/50-1/100) staining human VEGFD in human lung carcinoma tissue by immunohistochemistry using formalin fixed, paraffin embedded tissue.

    Ab63068 was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Anti-VEGFD antibody (ab63068)参考文献

ab63068 has not yet been referenced specifically in any publications.

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