RabMAb

Anti-VEGFB抗体[EPR4555] (ab110649)

概述

  • 产品名称Anti-VEGFB抗体[EPR4555]
    参阅全部 VEGFB 一抗
  • 描述
    兔单克隆抗体[EPR4555] to VEGFB
  • 经测试应用适用于: WBmore details
    不适用于: ICC,IHC-P or IP
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    A synthetic peptide corresponding to residues in Human VEGFB.

  • 阳性对照
    • VEGFB recombinant protein
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    A trial size is available to purchase for this antibody.

性能

应用

Our Abpromise guarantee covers the use of ab110649 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Detects a band of approximately 19 kDa (predicted molecular weight: 22 kDa).
  • 应用说明Is unsuitable for ICC,IHC-P or IP.
  • 靶标

    • 功能Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
    • 组织特异性Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.
    • 序列相似性Belongs to the PDGF/VEGF growth factor family.
    • 翻译后修饰VEGF-B186 is O-glycosylated.
    • 细胞定位Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
    • Information by UniProt
    • 数据库链接
    • 形式There are 2 isoforms produced by alternative splicing.
    • 别名
      • Vascular endothelial growth factor B antibody
      • VEGF B antibody
      • VEGF related factor antibody
      • VEGF-B antibody
      • VEGF-related factor antibody
      • Vegfb antibody
      • VEGFB_HUMAN antibody
      • VEGFL antibody
      • VRF antibody
      see all

    Anti-VEGFB antibody [EPR4555] 图像

    • Anti-VEGFB antibody [EPR4555] (ab110649) at 1/1000 dilution + VEGFB recombinant protein at 10 µg

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 22 kDa
      Observed band size : 19 kDa (why is the actual band size different from the predicted?)

    Anti-VEGFB antibody [EPR4555] (ab110649)参考文献

    ab110649 has not yet been referenced specifically in any publications.

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