概述

  • 产品名称Anti-VEGFB抗体
    参阅全部 VEGFB 一抗
  • 描述
    山羊多克隆抗体to VEGFB
  • 特异性Anti-human VEGFB exhibits less than 5% cross-reactivity with recombinant human VEGFD and no cross-reactivity with recombinant human VEGF and recombinant mouse VEGF.
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Recombinant full length VEGFB 186 (Human), expressed in E. coli.

  • 常规说明Do not store in a frost-free freezer. Endotoxin level is < 30 ng/mg antibody as determined by the LAL (Limulus amebocyte lysate) method.

性能

应用

Our Abpromise guarantee covers the use of ab10965 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明ELISA: Use at a concentration of 0.5 - 1 µg/ml. The detection limit for recombinant human VEGFB 167 is approximately 0.3 ng/well. The detection limit for recombinant human VEGFB 186 is approximately 0.03 ng/well.
    WB: Use at a concentration of 0.1 - 0.2 µg/ml. The detection limit for recombinant human VEGFB 167 is approximately 25 ng/lane under non-reducing and reducing conditions. The detection limit for recombinant human VEGFB 186 is approximately 5 ng/lane under non-reducing and reducing conditions. Predicted molecular weight: 22 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
    • 组织特异性Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.
    • 序列相似性Belongs to the PDGF/VEGF growth factor family.
    • 翻译后修饰VEGF-B186 is O-glycosylated.
    • 细胞定位Secreted. Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
    • Information by UniProt
    • 数据库链接
    • 形式There are 2 isoforms produced by alternative splicing.
    • 别名
      • Vascular endothelial growth factor B antibody
      • VEGF B antibody
      • VEGF related factor antibody
      • VEGF-B antibody
      • VEGF-related factor antibody
      • Vegfb antibody
      • VEGFB_HUMAN antibody
      • VEGFL antibody
      • VRF antibody
      see all

    Anti-VEGFB antibody (ab10965)参考文献

    ab10965 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"