Anti-VEGF Receptor 3抗体, prediluted (ab15295)

概述

  • 产品名称Anti-VEGF Receptor 3抗体, prediluted
    参阅全部 VEGF Receptor 3 一抗
  • 描述
    兔多克隆抗体to VEGF Receptor 3, prediluted
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive)(Human) (C terminal)

  • 阳性对照
    • Placenta, or Breast carcinoma.
  • 常规说明The concentration of this prediluted antibody is 2 µg/ml.

性能

应用

Our Abpromise guarantee covers the use of ab15295 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: Ready-to-use for 10 min at RT.
    Perform heat mediated antigen retrieval before commencing with IHC staining protocol(boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min).

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Receptor for VEGFC. Has a tyrosine-protein kinase activity.
    • 组织特异性Placenta, lung, heart, and kidney, does not seem to be expressed in pancreas and brain.
    • 疾病相关Defects in FLT4 are the cause of lymphedema hereditary type 1A (LMPH1A) [MIM:153100]; also known as Nonne-Milroy lymphedema or Milroy disease. Hereditary lymphedema is a chronic disabling condition which results in swelling of the extremities due to altered lymphatic flow. Patients with lymphedema suffer from recurrent local infections and physical impairment.
      Note=Defects in FLT4 are found in juvenile hemangioma. Juvenile hemangiomas are the most common tumors of infancy, occurring as many as 10% of all births. These benign vascular lesions enlarge rapidly during the first year of life by hyperplasia of endothelial cells and attendant pericytes, and then spontaneously involute over a period of years, leaving loose fibrofatty tissue.
    • 序列相似性Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
      Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
      Contains 1 protein kinase domain.
    • 细胞定位Membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • EC 2.7.10.1 antibody
      • flt 4 antibody
      • FLT-4 antibody
      • FLT4 antibody
      • FLT41 antibody
      • Fms related tyrosine kinase 4 antibody
      • Fms-like tyrosine kinase 4 antibody
      • LMPH1A antibody
      • PCL antibody
      • Soluble VEGFR3 variant 1 antibody
      • Soluble VEGFR3 variant 2 antibody
      • Soluble VEGFR3 variant 3 antibody
      • Tyrosine protein kinase receptor FLT4 antibody
      • Tyrosine-protein kinase receptor FLT4 antibody
      • Vascular endothelial growth factor receptor 3 antibody
      • Vascular endothelial growth factor receptor 3 precursor antibody
      • VEGF R3 antibody
      • VEGFR 3 antibody
      • VEGFR-3 antibody
      • VEGFR3 antibody
      • VGFR3_HUMAN antibody
      see all

    Anti-VEGF Receptor 3 antibody, prediluted 图像

    • ab15295 staining VEGF Receptor in human placenta by Immunohistochemistry (FFPE-sections).
    • ab15295 staining VEGF Receptor in human placenta by Immunohistochemistry (FFPE-sections).

    Anti-VEGF Receptor 3 antibody, prediluted (ab15295)参考文献

    This product has been referenced in:
    • Linthicum FH  et al. The periductal channels of the endolymphatic duct, hydrodynamic implications. Otolaryngol Head Neck Surg 150:441-7 (2014). Human . Read more (PubMed: 24376120) »

    See 1 Publication for this product

    Product Wall

    Application Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
    Blocking step H2O2 as blocking agent for 10 minute(s) · Concentration: 3% · Temperature: 25°C
    Antigen retrieval step Heat mediated - Buffer/Enzyme Used: citrate pH6, 20 min at 100C
    Sample Human Tissue sections (Osteosarcoma, Breast Carcinoma)
    Specification Osteosarcoma, Breast Carcinoma
    Permeabilization No
    Fixative Formaldehyde
    Username

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    提交于 Feb 26 2015

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"