Anti-VDAC2抗体(ab118872)

概述

  • 产品名称Anti-VDAC2抗体
    参阅全部 VDAC2 一抗
  • 描述
    山羊多克隆抗体to VDAC2
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Cow, Dog, Pig
  • 免疫原

    Synthetic peptide

    GHKVGLALELEA

    , corresponding to C terminal amino acids 298-309 of Human VDAC2 Isoform 1.

  • 阳性对照
    • Human testis lysate, Human heart tissue.

性能

应用

Our Abpromise guarantee covers the use of ab118872 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 32 kDa.
ELISA 1/64000.
IHC-P Use a concentration of 2.5 - 5 µg/ml.

靶标

  • 功能Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective.
  • 组织特异性Expressed in all tissues examined.
  • 序列相似性Belongs to the eukaryotic mitochondrial porin family.
  • 结构域Consists mainly of a membrane-spanning beta-barrel formed by 19 beta-strands.
  • 细胞定位Mitochondrion outer membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • B-36 vdac antibody
    • FLJ23841 antibody
    • hVDAC2 antibody
    • OTTHUMP00000019878 antibody
    • OTTHUMP00000019879 antibody
    • OTTHUMP00000019880 antibody
    • Outer mitochondrial membrane protein porin 2 antibody
    • POR antibody
    • Porin-2 antibody
    • VDAC 2 antibody
    • VDAC-2 antibody
    • VDAC2 antibody
    • VDAC2_HUMAN antibody
    • Vdac6 antibody
    • Voltage dependent anion channel 2 antibody
    • Voltage dependent anion selective channel protein 2 antibody
    • Voltage-dependent anion-selective channel protein 2 antibody
    see all

Anti-VDAC2 antibody 图像

  • Immunohistochemical staining of ab118872 at 5 µg/ml staining VDAC2 in Paraffin-embedded Human heart tissue followed by biotinylated anti-Goat IgG secondary antibody, alkaline phosphatasestreptavidin and chromogen
  • Anti-VDAC2 antibody (ab118872) at 0.3 µg/ml + Human testis lysate in RIPA buffer at 35 µg
    Developed using the ECL technique

    Predicted band size : 32 kDa

Anti-VDAC2 antibody (ab118872)参考文献

ab118872 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting us. Unfortunately, both VDAC1 and VDAC3 are very homologous with VDAC2. While we have not tested these antibodies specifically for cross-reactivity with VDAC1 and VDAC3, the antibodies ab37985 and ab118872 show ˜67% homology wi...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"