概述

  • 产品名称Anti-VDAC1/Porin抗体
    参阅全部 VDAC1/Porin 一抗
  • 描述
    兔多克隆抗体to VDAC1/Porin
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rabbit, Cow, Pig
  • 免疫原

    Recombinant fragment corresponding to Human VDAC1/Porin aa 1-181.

  • 阳性对照
    • A431, H1299, HeLa and HepG2 cell lysates

性能

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应用

Our Abpromise guarantee covers the use of ab97851 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 31 kDa.

靶标

  • 功能Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
  • 组织特异性Heart, liver and skeletal muscle.
  • 序列相似性Belongs to the eukaryotic mitochondrial porin family.
  • 结构域Consists mainly of a membrane-spanning beta-barrel formed by 19 beta-strands. The helical N-terminus folds back into the pore opening and plays a role in voltage-gated channel activity.
  • 细胞定位Mitochondrion outer membrane. Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • N2441 antibody
    • OMP2 antibody
    • POR1 antibody
    • hVDAC1 antibody
    • MGC111064 antibody
    • Mitochondrial Porin antibody
    • Outer mitochondrial membrane protein porin 1 antibody
    • Plasmalemmal porin antibody
    • Porin 31HL antibody
    • Porin 31HM antibody
    • VDAC antibody
    • VDAC-1 antibody
    • Vdac1 antibody
    • VDAC1_HUMAN antibody
    • Voltage dependent anion channel 1 antibody
    • Voltage dependent anion selective channel protein 1 antibody
    • Voltage-dependent anion-selective channel protein 1 antibody
    • YNL055C antibody
    • YNL2441C antibody
    see all

Anti-VDAC1/Porin antibody 图像

  • Anti-VDAC1/Porin antibody (ab97851) at 1/1000 dilution + A431 whole cell lysate at 30 µg

    Predicted band size : 31 kDa
    12% SDS-PAGE.

Anti-VDAC1/Porin antibody (ab97851)参考文献

ab97851 has not yet been referenced specifically in any publications.

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