概述

  • 产品名称Anti-VCAM1抗体[STA]
    参阅全部 VCAM1 一抗
  • 描述
    小鼠单克隆抗体[STA] to VCAM1
  • 经测试应用适用于: IP, ELISA, IHC-Fr, Flow Cytmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Human DS6 T cell line

  • 阳性对照
    • Flow Cyt: TNF-alpha activated HUVEC cells

性能

应用

Our Abpromise guarantee covers the use of ab95139 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration. Acetone fixation
Flow Cyt Use a concentration of 6 µg/ml. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

靶标

  • 功能Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
  • 组织特异性Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.
  • 序列相似性Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
  • 结构域Either the first or the fourth Ig-like C2-type domain is required for VLA4-dependent cell adhesion.
  • 翻译后修饰Sialoglycoprotein.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD106 antibody
    • CD106 Antigen antibody
    • INCAM 100 antibody
    • INCAM-100 antibody
    • L1CAM antibody
    • MGC99561 antibody
    • V-CAM 1 antibody
    • Vascular Cell Adhesion Molecule 1 antibody
    • Vascular cell adhesion protein 1 antibody
    • VCAM 1 antibody
    • VCAM-1 antibody
    • VCAM1 antibody
    • VCAM1_HUMAN antibody
    see all

Anti-VCAM1 antibody [STA] (ab95139)参考文献

This product has been referenced in:
  • Yen YT  et al. Modeling the early events of severe acute respiratory syndrome coronavirus infection in vitro. J Virol 80:2684-93 (2006). Read more (PubMed: 16501078) »

See 1 Publication for this product

Product Wall

Abreviews
Application ELISA
Sample Human Serum (cardiovascular biomarker)
Specification cardiovascular biomarker
Blocking step BSA as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 3% · Temperature: 20°C
Type Sandwich (Detection)
Username

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提交于 Mar 13 2013

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Effectively all of the products mentioned are suitable, and therefore are guaranteed for IHC in frozen sections in the species stated on their datasheets.

However, instead of using PFA as a fixative, I w...

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