Anti-VCAM1抗体[MR106] (Biotin) (ab95542)

概述

  • 产品名称
    Anti-VCAM1抗体[MR106] (Biotin)
    参阅全部 VCAM1 一抗
  • 描述
    小鼠单克隆抗体[MR106] to VCAM1 (Biotin)
  • 宿主
    Mouse
  • 偶联物
    Biotin
  • 经测试应用
    适用于: Flow Cytmore details
  • 种属反应性
    与反应: Rat
  • 免疫原

    Rat VCAM1 transfected L5178Y cells.

  • 阳性对照
    • Rat bone marrow cells

应用

Our Abpromise guarantee covers the use of ab95542 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 0.125-0.25µg for 105-8 cells.

A final volume of 100 µL is recommended for staining the cell sample.
ab18434 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

靶标

  • 功能
    Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
  • 组织特异性
    Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.
  • 序列相似性
    Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
  • 结构域
    Either the first or the fourth Ig-like C2-type domain is required for VLA4-dependent cell adhesion.
  • 翻译后修饰
    Sialoglycoprotein.
  • 细胞定位
    Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD106 antibody
    • CD106 Antigen antibody
    • INCAM 100 antibody
    • INCAM-100 antibody
    • L1CAM antibody
    • MGC99561 antibody
    • V-CAM 1 antibody
    • Vascular Cell Adhesion Molecule 1 antibody
    • Vascular cell adhesion protein 1 antibody
    • VCAM 1 antibody
    • VCAM-1 antibody
    • VCAM1 antibody
    • VCAM1_HUMAN antibody
    see all

图片

  • Staining of Rat bone marrow cells with 0.125 µg of Mouse IgG1 ? Isotype Control Biotin (left) or 0.125 µg of ab95542 (right), followed by Streptavidin PE.
    Total viable cells were used for analysis.

文献

ab95542 has not yet been referenced specifically in any publications.

客户评价及客户问答

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