Anti-VCAM1抗体[MR106] (Biotin) (ab95542)

概述

  • 产品名称Anti-VCAM1抗体[MR106] (Biotin)
    参阅全部 VCAM1 一抗
  • 描述
    小鼠单克隆抗体[MR106] to VCAM1 (Biotin)
  • 偶联物Biotin
  • 经测试应用适用于: Flow Cytmore details
  • 种属反应性
    与反应: Rat
  • 免疫原

    Rat VCAM1 transfected L5178Y cells.

  • 阳性对照
    • Rat bone marrow cells

应用

Our Abpromise guarantee covers the use of ab95542 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Flow Cyt Use 0.125-0.25µg for 105-8 cells.

A final volume of 100 µL is recommended for staining the cell sample.
ab18434 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

靶标

  • 功能Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with the beta-1 integrin VLA4 on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/VLA4 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
  • 组织特异性Expressed on inflammed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflammed tissue.
  • 序列相似性Contains 7 Ig-like C2-type (immunoglobulin-like) domains.
  • 结构域Either the first or the fourth Ig-like C2-type domain is required for VLA4-dependent cell adhesion.
  • 翻译后修饰Sialoglycoprotein.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CD106 antibody
    • CD106 Antigen antibody
    • INCAM 100 antibody
    • INCAM-100 antibody
    • L1CAM antibody
    • MGC99561 antibody
    • V-CAM 1 antibody
    • Vascular Cell Adhesion Molecule 1 antibody
    • Vascular cell adhesion protein 1 antibody
    • VCAM 1 antibody
    • VCAM-1 antibody
    • VCAM1 antibody
    • VCAM1_HUMAN antibody
    see all

Anti-VCAM1 antibody [MR106] (Biotin) 图像

  • Staining of Rat bone marrow cells with 0.125 µg of Mouse IgG1 ? Isotype Control Biotin (left) or 0.125 µg of ab95542 (right), followed by Streptavidin PE.
    Total viable cells were used for analysis.

Anti-VCAM1 antibody [MR106] (Biotin) (ab95542)参考文献

ab95542 has not yet been referenced specifically in any publications.

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